NS1BP

Details:

UniProt Entry: Q9Y6Y0
Gene: IVNS1ABP
Class: Other E3 Components
Family: Adaptor
Protein length: 642
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9Y6Y0
MIPNGYLMFE DENFIESSVA KLNALRKSGQ FCDVRLQVCG HEMLAHRAVL ACCSPYLFEI
FNSDSDPHGI SHVKFDDLNP EAVEVLLNYA YTAQLKADKE LVKDVYSAAK KLKMDRVKQV
CGDYLLSRMD VTSCISYRNF ASCMGDSRLL NKVDAYIQEH LLQISEEEEF LKLPRLKLEV
MLEDNVCLPS NGKLYTKVIN WVQRSIWENG DSLEELMEEV QTLYYSADHK LLDGNLLDGQ
AEVFGSDDDH IQFVQKKPPR ENGHKQISSS STGCLSSPNA TVQSPKHEWK IVASEKTSNN
TYLCLAVLDG IFCVIFLHGR NSPQSSPTST PKLSKSLSFE MQQDELIEKP MSPMQYARSG
LGTAEMNGKL IAAGGYNREE CLRTVECYNP HTDHWSFLAP MRTPRARFQM AVLMGQLYVV
GGSNGHSDDL SCGEMYDSNI DDWIPVPELR TNRCNAGVCA LNGKLYIVGG SDPYGQKGLK
NCDVFDPVTK LWTSCAPLNI RRHQSAVCEL GGYLYIIGGA ESWNCLNTVE RYNPENNTWT
LIAPMNVARR GAGVAVLNGK LFVCGGFDGS HAISCVEMYD PTRNEWKMMG NMTSPRSNAG
IATVGNTIYA VGGFDGNEFL NTVEVYNLES NEWSPYTKIF QF

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	607	Family	BTB-kelch protein	IPR017096	PIRSF037037
9	136	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
9	127	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
22	126	Domain	BTB/POZ domain	IPR000210	PF00651
32	99	Domain	BTB/POZ domain	IPR000210	PS50097
32	129	Domain	BTB/POZ domain	IPR000210	SM00225
134	233	Domain	BTB/Kelch-associated	IPR011705	SM00875
134	221	Domain	BTB/Kelch-associated	IPR011705	PF07707
236	474	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
328	473	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
357	402	Repeat	Kelch repeat type 1	IPR006652	PF01344
369	415	Repeat	Kelch repeat type 1	IPR006652	SM00612
404	450	Repeat	Kelch repeat type 1	IPR006652	PF01344
416	463	Repeat	Kelch repeat type 1	IPR006652	SM00612
430	636	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
453	499	Repeat	Kelch repeat type 1	IPR006652	PF01344
464	512	Repeat	Kelch repeat type 1	IPR006652	SM00612
475	640	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
501	546	Repeat	Kelch repeat type 1	IPR006652	PF01344
513	559	Repeat	Kelch repeat type 1	IPR006652	SM00612
548	592	Repeat	Kelch repeat type 1	IPR006652	PF01344
560	606	Repeat	Kelch repeat type 1	IPR006652	SM00612
583	641	Family	BTB-kelch protein	IPR017096	PIRSF037037
595	635	Repeat	Kelch repeat type 1	IPR006652	PF01344
607	641	Repeat	Kelch repeat type 1	IPR006652	SM00612

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0097193	intrinsic apoptotic signaling pathway	Biological Process	IEA	GO_REF:0000107
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	Biological Process	IEA	GO_REF:0000107
GO:0006383	transcription by RNA polymerase III	Biological Process	TAS	PMID:9696811
GO:0006397	mRNA processing	Biological Process	IEA	GO_REF:0000043
GO:0008380	RNA splicing	Biological Process	IEA	GO_REF:0000043
GO:0009615	response to virus	Biological Process	IMP	PMID:23825951
GO:0031397	negative regulation of protein ubiquitination	Biological Process	IMP	PMID:25619834
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0005654	nucleoplasm	Cellular Component	IEA	GO_REF:0000044
GO:0005829	cytosol	Cellular Component	IDA	GO_REF:0000052
GO:0005856	cytoskeleton	Cellular Component	IEA	GO_REF:0000120
GO:0005667	transcription regulator complex	Cellular Component	TAS	PMID:9696811
GO:0005681	spliceosomal complex	Cellular Component	TAS	PMID:9696811
GO:0031463	Cul3-RING ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:23825951
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IBA	GO_REF:0000033
GO:0003677	DNA binding	Molecular Function	IEA	GO_REF:0000043
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043

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