ASB1

Details:

UniProt Entry: Q9Y576
Gene: ASB1
Class: Other E3 Components
Family: Receptor
Protein length: 335
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9Y576
MAEGGSPDGR AGPGSAGRNL KEWLREQFCD HPLEHCEDTR LHDAAYVGDL QTLRSLLQEE
SYRSRINEKS VWCCGWLPCT PLRIAATAGH GSCVDFLIRK GAEVDLVDVK GQTALYVAVV
NGHLESTQIL LEAGADPNGS RHHRSTPVYH ASRVGRADIL KALIRYGADV DVNHHLTPDV
QPRFSRRLTS LVVCPLYISA AYHNLQCFRL LLLAGANPDF NCNGPVNTQG FYRGSPGCVM
DAVLRHGCEA AFVSLLVEFG ANLNLVKWES LGPESRGRRK VDPEALQVFK EARSVPRTLL
CLCRVAVRRA LGKHRLHLIP SLPLPDPIKK FLLHE

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
29	271	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	SSF48403
32	278	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
36	68	Repeat	Ankyrin repeat	IPR002110	SM00248
41	138	Repeat	Ankyrin repeat	IPR002110	PF12796
77	106	Repeat	Ankyrin repeat	IPR002110	SM00248
80	109	Repeat	Ankyrin repeat	IPR002110	PS50088
110	142	Repeat	Ankyrin repeat	IPR002110	PS50088
110	139	Repeat	Ankyrin repeat	IPR002110	SM00248
111	126	Repeat	Ankyrin repeat	IPR002110	PR01415
143	172	Repeat	Ankyrin repeat	IPR002110	SM00248
143	175	Repeat	Ankyrin repeat	IPR002110	PS50088
159	173	Repeat	Ankyrin repeat	IPR002110	PR01415
195	220	Repeat	Ankyrin repeat	IPR002110	SM00248
288	333	Homologous_superfamily	SOCS box-like domain superfamily	IPR036036	SSF158235
293	335	Domain	SOCS box domain	IPR001496	PS50225
294	335	Domain	Ankyrin repeat and SOCS box protein 1, SOCS box domain	IPR037331	cd03720
296	333	Domain	SOCS box domain	IPR001496	PF07525
296	335	Domain	SOCS box domain	IPR001496	SM00969

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0035556	intracellular signal transduction	Biological Process	IEA	GO_REF:0000002
GO:0030539	male genitalia development	Biological Process	IEA	GO_REF:0000107
GO:0001818	negative regulation of cytokine production	Biological Process	NAS	PMID:11111040
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000117
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0000151	ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IDA	PMID:16325183
GO:0005515	protein binding	Molecular Function	IPI	PMID:16325183
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IBA	GO_REF:0000033

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