ASB4

Details:

UniProt Entry: Q9Y574
Gene: ASB4
Class: Other E3 Components
Family: Receptor
Protein length: 426
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9Y574
MDGTTAPVTK SGAAKLVKRN FLEALKSNDF GKLKAILIQR QIDVDTVFEV EDENMVLASY
KQGYWLPSYK LKSSWATGLH LSVLFGHVEC LLVLLDHNAT INCRPNGKTP LHVACEMANV
DCVKILCDRG AKLNCYSLSG HTALHFCTTP SSILCAKQLV WRGANVNMKT NNQDEETPLH
TAAHFGLSEL VAFYVEHGAI VDSVNAHMET PLAIAAYWAL RFKEQEYSTE HHLVCRMLLD
YKAEVNARDD DFKSPLHKAA WNCDHVLMHM MLEAGAEANL MDINGCAAIQ YVLKVTSVRP
AAQPEICYQL LLNHGAARIY PPQFHKVIQA CHSCPKAIEV VVNAYEHIRW NTKWRRAIPD
DDLEKYWDFY HSLFTVCCNS PRTLMHLSRC AIRRTLHNRC HRAIPLLSLP LSLKKYLLLE
PEGIIY

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
13	171	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
22	295	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	SSF48403
74	103	Repeat	Ankyrin repeat	IPR002110	SM00248
74	106	Repeat	Ankyrin repeat	IPR002110	PS50088
79	169	Repeat	Ankyrin repeat	IPR002110	PF12796
106	138	Repeat	Ankyrin repeat	IPR002110	PS50088
106	135	Repeat	Ankyrin repeat	IPR002110	SM00248
139	171	Repeat	Ankyrin repeat	IPR002110	PS50088
139	168	Repeat	Ankyrin repeat	IPR002110	SM00248
172	321	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
174	206	Repeat	Ankyrin repeat	IPR002110	PS50088
174	203	Repeat	Ankyrin repeat	IPR002110	SM00248
207	247	Repeat	Ankyrin repeat	IPR002110	SM00248
251	280	Repeat	Ankyrin repeat	IPR002110	SM00248
251	283	Repeat	Ankyrin repeat	IPR002110	PS50088
374	421	Homologous_superfamily	SOCS box-like domain superfamily	IPR036036	SSF158235
379	417	Domain	SOCS box domain	IPR001496	PS50225
380	418	Domain	SOCS box domain	IPR001496	PF07525
381	420	Domain	SOCS box domain	IPR001496	SM00969

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0035556	intracellular signal transduction	Biological Process	IEA	GO_REF:0000002
GO:0051865	protein autoubiquitination	Biological Process	ISS	GO_REF:0000024
GO:2001214	positive regulation of vasculogenesis	Biological Process	ISS	GO_REF:0000024
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000117
GO:0031462	Cul2-RING ubiquitin ligase complex	Cellular Component	IEA	GO_REF:0000120
GO:0031466	Cul5-RING ubiquitin ligase complex	Cellular Component	IEA	GO_REF:0000120
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	ISS	GO_REF:0000024
GO:0019899	enzyme binding	Molecular Function	IEA	GO_REF:0000107
GO:0031625	ubiquitin protein ligase binding	Molecular Function	ISS	GO_REF:0000024
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000107

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