UB2J1

Details:

UniProt Entry: Q9Y385
Gene: UBE2J1
Class: Other E3 Components
Family: E2
Protein length: 318
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9Y385
METRYNLKSP AVKRLMKEAA ELKDPTDHYH AQPLEDNLFE WHFTVRGPPD SDFDGGVYHG
RIVLPPEYPM KPPSIILLTA NGRFEVGKKI CLSISGHHPE TWQPSWSIRT ALLAIIGFMP
TKGEGAIGSL DYTPEERRAL AKKSQDFCCE GCGSAMKDVL LPLKSGSDSS QADQEAKELA
RQISFKAEVN SSGKTISESD LNHSFSLTDL QDDIPTTFQG ATASTSYGLQ NSSAASFHQP
TQPVAKNTSM SPRQRRAQQQ SQRRLSTSPD VIQGHQPRDN HTDHGGSAVL IVILTLALAA
LIFRRIYLAN EYIFDFEL

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
2	184	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	G3DSA:3.10.110.10
10	160	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PS50127
11	160	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	SSF54495
12	119	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	cd00195
14	120	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PF00179

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0007286	spermatid development	Biological Process	IEA	GO_REF:0000107
GO:0010935	regulation of macrophage cytokine production	Biological Process	IEA	GO_REF:0000107
GO:0032680	regulation of tumor necrosis factor production	Biological Process	IEA	GO_REF:0000107
GO:0036503	ERAD pathway	Biological Process	IEA	GO_REF:0000120
GO:0000209	protein polyubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0018279	protein N-linked glycosylation via asparagine	Biological Process	IMP	PMID:22607976
GO:1904153	negative regulation of retrograde protein transport, ER to cytosol	Biological Process	IMP	PMID:25660456
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IDA	PMID:33472082
GO:0005783	endoplasmic reticulum	Cellular Component	IEA	GO_REF:0000043
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0000836	Hrd1p ubiquitin ligase complex	Cellular Component	IDA	PMID:28827405
GO:0000166	nucleotide binding	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:19690564
GO:0005524	ATP binding	Molecular Function	IEA	GO_REF:0000043
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0031625	ubiquitin protein ligase binding	Molecular Function	IPI	PMID:11439185
GO:0061631	ubiquitin conjugating enzyme activity	Molecular Function	IEA	GO_REF:0000003

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