RNF24

Details:

UniProt Entry: Q9Y225
Gene: RNF24
Class: RING
Family: RING4
Protein length: 148
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link
PDB Structures: 2ep4

Protein Sequence ▾

>Q9Y225
MSSDFPHYNF RMPNIGFQNL PLNIYIVVFG TAIFVFILSL LFCCYLIRLR HQAHKEFYAY
KQVILKEKVK ELNLHELCAV CLEDFKPRDE LGICPCKHAF HRKCLIKWLE VRKVCPLCNM
PVLQLAQLHS KQDRGPPQGP LPGAENIV

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
47	123	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
77	119	Domain	Zinc finger, RING-CH-type	IPR011016	SM00744
78	118	Domain	Zinc finger, RING-type	IPR001841	SM00184
78	119	Domain	Zinc finger, RING-type	IPR001841	PF13639
78	119	Domain	Zinc finger, RING-type	IPR001841	PS50089

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0000139	Golgi membrane	Cellular Component	IEA	GO_REF:0000044
GO:0005794	Golgi apparatus	Cellular Component	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:25416956
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043

Enzyme–Substrate Interactions ▾

Data Usage Statement and License Agreement

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The E3 Ligome database, including all associated data, metadata, and documentation, is the intellectual property of Goethe University (PROXIDRUGs consortium) under the InnoDATA project.
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If you use or refer to the Database in your publications, reports, or presentations, you must cite the paper: Dutta, A., Cristiani, A., Nikte, S.V. et al. Multi-scale classification decodes the complexity of the human E3 ligome. Nat Commun 16, 11382 (2025).

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Email: bhaskara@med.uni-frankfurt.de.
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