WDR3

Details:

UniProt Entry: Q9UNX4
Gene: WDR3
Class: Other E3 Components
Family: Adaptor
Protein length: 943
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9UNX4
MGLTKQYLRY VASAVFGVIG SQKGNIVFVT LRGEKGRYVA VPACEHVFIW DLRKGEKILI
LQGLKQEVTC LCPSPDGLHL AVGYEDGSIR IFSLLSGEGN VTFNGHKAAI TTLKYDQLGG
RLASGSKDTD IIVWDVINES GLYRLKGHKD AITQALFLRE KNLLVTSGKD TMVKWWDLDT
QHCFKTMVGH RTEVWGLVLL SEEKRLITGA SDSELRVWDI AYLQEIEDPE EPDPKKIKGS
SPGIQDTLEA EDGAFETDEA PEDRILSCRK AGSIMREGRD RVVNLAVDKT GRILACHGTD
SVLELFCILS KKEIQKKMDK KMKKARKKAK LHSSKGEEED PEVNVEMSLQ DEIQRVTNIK
TSAKIKSFDL IHSPHGELKA VFLLQNNLVE LYSLNPSLPT PQPVRTSRIT IGGHRSDVRT
LSFSSDNIAV LSAAADSIKI WNRSTLQCIR TMTCEYALCS FFVPGDRQVV IGTKTGKLQL
YDLASGNLLE TIDAHDGALW SMSLSPDQRG FVTGGADKSV KFWDFELVKD ENSTQKRLSV
KQTRTLQLDE DVLCVSYSPN QKLLAVSLLD CTVKIFYVDT LKFFLSLYGH KLPVICMDIS
HDGALIATGS ADRNVKIWGL DFGDCHKSLF AHDDSVMYLQ FVPKSHLFFT AGKDHKIKQW
DADKFEHIQT LEGHHQEIWC LAVSPSGDYV VSSSHDKSLR LWERTREPLI LEEEREMERE
AEYEESVAKE DQPAVPGETQ GDSYFTGKKT IETVKAAERI MEAIELYREE TAKMKEHKAI
CKAAGKEVPL PSNPILMAYG SISPSAYVLE IFKGIKSSEL EESLLVLPFS YVPDILKLFN
EFIQLGSDVE LICRCLFFLL RIHFGQITSN QMLVPVIEKL RETTISKVSQ VRDVIGFNMA
GLDYLKRECE AKSEVMFFAD ATSHLEEKKR KRKKREKLIL TLT

Domain Architecture (From InterPro) ▾

The same domains may appear in multiple rows, following InterPro convention.

Start	End	Type	Name	InterPro	Source
13	222	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	IPR015943	G3DSA:2.130.10.10
36	315	Homologous_superfamily	WD40-repeat-containing domain superfamily	IPR036322	SSF50978
54	93	Repeat	WD40 repeat	IPR001680	SM00320
61	115	Domain	Anaphase-promoting complex subunit 4, WD40 domain	IPR024977	PF12894
61	102	Repeat	WD40 repeat	IPR001680	PS50082
96	135	Repeat	WD40 repeat	IPR001680	SM00320
103	144	Repeat	WD40 repeat	IPR001680	PS50082
122	136	Repeat	G-protein beta WD-40 repeat	IPR020472	PR00320
122	136	Conserved_site	WD40 repeat, conserved site	IPR019775	PS00678
138	177	Repeat	WD40 repeat	IPR001680	SM00320
142	177	Repeat	WD40 repeat	IPR001680	PF00400
145	186	Repeat	WD40 repeat	IPR001680	PS50082
180	219	Repeat	WD40 repeat	IPR001680	SM00320
182	219	Repeat	WD40 repeat	IPR001680	PF00400
187	228	Repeat	WD40 repeat	IPR001680	PS50082
206	220	Conserved_site	WD40 repeat, conserved site	IPR019775	PS00678
206	220	Repeat	G-protein beta WD-40 repeat	IPR020472	PR00320
279	456	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	IPR015943	G3DSA:2.130.10.10
400	442	Repeat	WD40 repeat	IPR001680	SM00320
410	442	Repeat	WD40 repeat	IPR001680	PF00400
411	451	Repeat	WD40 repeat	IPR001680	PS50082
445	482	Repeat	WD40 repeat	IPR001680	SM00320
457	648	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	IPR015943	G3DSA:2.130.10.10
485	524	Repeat	WD40 repeat	IPR001680	SM00320
487	524	Repeat	WD40 repeat	IPR001680	PF00400
492	526	Repeat	WD40 repeat	IPR001680	PS50082
511	525	Repeat	G-protein beta WD-40 repeat	IPR020472	PR00320
539	577	Repeat	WD40 repeat	IPR001680	SM00320
580	619	Repeat	WD40 repeat	IPR001680	SM00320
586	618	Repeat	WD40 repeat	IPR001680	PF00400
587	628	Repeat	WD40 repeat	IPR001680	PS50082
622	661	Repeat	WD40 repeat	IPR001680	SM00320
624	661	Repeat	WD40 repeat	IPR001680	PF00400
629	670	Repeat	WD40 repeat	IPR001680	PS50082
649	715	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	IPR015943	G3DSA:2.130.10.10
664	703	Repeat	WD40 repeat	IPR001680	SM00320
666	702	Repeat	WD40 repeat	IPR001680	PF00400
671	703	Repeat	WD40 repeat	IPR001680	PS50082
806	906	Domain	Small-subunit processome, Utp12	IPR007148	PF04003

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0030490	maturation of SSU-rRNA	Biological Process	IBA	GO_REF:0000033
GO:0042274	ribosomal small subunit biogenesis	Biological Process	IDA	PMID:34516797
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000043
GO:0005654	nucleoplasm	Cellular Component	IDA	GO_REF:0000052
GO:0005730	nucleolus	Cellular Component	IEA	GO_REF:0000044
GO:0031965	nuclear membrane	Cellular Component	IDA	GO_REF:0000052
GO:0032040	small-subunit processome	Cellular Component	IBA	GO_REF:0000033
GO:0034388	Pwp2p-containing subcomplex of 90S preribosome	Cellular Component	IBA	GO_REF:0000033
GO:0003723	RNA binding	Molecular Function	HDA	PMID:22658674
GO:0030515	snoRNA binding	Molecular Function	IBA	GO_REF:0000033

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