APC10

Details:

UniProt Entry: Q9UM13
Gene: ANAPC10
Class: Other E3 Components
Family: Adaptor
Protein length: 185
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9UM13
MTTPNKTPPG ADPKQLERTG TVREIGSQAV WSLSSCKPGF GVDQLRDDNL ETYWQSDGSQ
PHLVNIQFRR KTTVKTLCIY ADYKSDESYT PSKISVRVGN NFHNLQEIRQ LELVEPSGWI
HVPLTDNHKK PTRTFMIQIA VLANHQNGRD THMRQIKIYT PVEESSIGKF PRCTTIDFMM
YRSIR

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	185	Domain	APC10/DOC domain	IPR004939	PS51284
2	185	Family	Anaphase-promoting complex subunit APC10/Doc1	IPR016901	PTHR12936
2	185	Family	Anaphase-promoting complex subunit APC10/Doc1	IPR016901	PIRSF028841
6	182	Domain	APC10/DOC domain	IPR004939	PF03256
11	160	Homologous_superfamily	Galactose-binding-like domain superfamily	IPR008979	SSF49785
22	184	Domain	APC10/DOC domain	IPR004939	SM01337
23	160	Family	Anaphase-promoting complex subunit APC10/Doc1	IPR016901	cd08366

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0031145	anaphase-promoting complex-dependent catabolic process	Biological Process	IEA	GO_REF:0000002
GO:0051301	cell division	Biological Process	IEA	GO_REF:0000043
GO:0007346	regulation of mitotic cell cycle	Biological Process	NAS	PMID:15678131
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0051445	regulation of meiotic cell cycle	Biological Process	NAS	PMID:15678131
GO:0070936	protein K48-linked ubiquitination	Biological Process	IDA	PMID:29033132
GO:0070979	protein K11-linked ubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0141198	protein branched polyubiquitination	Biological Process	IDA	PMID:29033132
GO:0005680	anaphase-promoting complex	Cellular Component	IEA	GO_REF:0000002
GO:0005654	nucleoplasm	Cellular Component	TAS	Reactome:R-HSA-174057
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000107
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-141423
GO:0005515	protein binding	Molecular Function	IPI	PMID:34595750

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