FBXL3

Details:

UniProt Entry: Q9UKT7
Gene: FBXL3
Class: Other E3 Components
Family: Receptor
Protein length: 428
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9UKT7
MKRGGRDSDR NSSEEGTAEK SKKLRTTNEH SQTCDWGNLL QDIILQVFKY LPLLDRAHAS
QVCRNWNQVF HMPDLWRCFE FELNQPATSY LKATHPELIK QIIKRHSNHL QYVSFKVDSS
KESAEAACDI LSQLVNCSLK TLGLISTARP SFMDLPKSHF ISALTVVFVN SKSLSSLKID
DTPVDDPSLK VLVANNSDTL KLLKMSSCPH VSPAGILCVA DQCHGLRELA LNYHLLSDEL
LLALSSEKHV RLEHLRIDVV SENPGQTHFH TIQKSSWDAF IRHSPKVNLV MYFFLYEEEF
DPFFRYEIPA THLYFGRSVS KDVLGRVGMT CPRLVELVVC ANGLRPLDEE LIRIAERCKN
LSAIGLGECE VSCSAFVEFV KMCGGRLSQL SIMEEVLIPD QKYSLEQIHW EVSKHLGRVW
FPDMMPTW

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
32	116	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
39	79	Domain	F-box domain	IPR001810	SM00256
42	77	Domain	F-box domain	IPR001810	PF12937
77	428	Homologous_superfamily	Leucine-rich repeat domain superfamily	IPR032675	G3DSA:3.80.10.10

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	ISS	GO_REF:0000024
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IEA	GO_REF:0000107
GO:0031648	protein destabilization	Biological Process	ISS	GO_REF:0000024
GO:0042752	regulation of circadian rhythm	Biological Process	IEA	GO_REF:0000120
GO:0043153	entrainment of circadian clock by photoperiod	Biological Process	ISS	GO_REF:0000024
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IEA	GO_REF:0000107
GO:0048511	rhythmic process	Biological Process	IEA	GO_REF:0000043
GO:0016604	nuclear body	Cellular Component	IDA	GO_REF:0000052
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005829	cytosol	Cellular Component	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0000151	ubiquitin ligase complex	Cellular Component	NAS	PMID:10531035
GO:0019005	SCF ubiquitin ligase complex	Cellular Component	IDA	PMID:17463251
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IEA	GO_REF:0000107
GO:0005515	protein binding	Molecular Function	IPI	PMID:17463251

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