FBX10

Details:

UniProt Entry: Q9UK96
Gene: FBXO10
Class: Other E3 Components
Family: Receptor
Protein length: 956
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9UK96
MEAGGLPLEL WRMILAYLHL PDLGRCSLVC RAWYELILSL DSTRWRQLCL GCTECRHPNW
PNQPDVEPES WREAFKQHYL ASKTWTKNAL DLESSICFSL FRRRRERRTL SVGPGREFDS
LGSALAMASL YDRIVLFPGV YEEQGEIILK VPVEIVGQGK LGEVALLASI DQHCSTTRLC
NLVFTPAWFS PIMYKTTSGH VQFDNCNFEN GHIQVHGPGT CQVKFCTFKN THIFLHNVPL
CVLENCEFVG SENNSVTVEG HPSADKNWAY KYLLGLIKSS PTFLPTEDSD FLMSLDLESR
DQAWSPKTCD IVIEGSQSPT SPASSSPKPG SKAGSQEAEV GSDGERVAQT PDSSDGGLSP
SGEDEDEDQL MYRLSYQVQG PRPVLGGSFL GPPLPGASIQ LPSCLVLNSL QQELQKDKEA
MALANSVQGC LIRKCLFRDG KGGVFVCSHG RAKMEGNIFR NLTYAVRCIH NSKIIMLRND
IYRCRASGIF LRLEGGGLIA GNNIYHNAEA GVDIRKKSNP LILCNQIHHG LRSGIVVLGN
GKGIIRNNQI FSNKEAGIYI LYHGNPVVSG NHIFKGRAAG IAVNENGKGL ITENVIRENQ
WGGVDIRRGG IPVLRSNLIC FGYSDGVVVG DEGKGLIEGN TIYANKGCGV WMMSSSLPHV
TSNHVSYNGL YGVAVFSQKD GSSELPRGHR AQENFSEDGD AILWETELEK EDDPLRRPIT
IALVESNSIN HNGASGLYVQ SSEALHVITN VIHANGDRGI TVAQSSQPTR VANNSISCNR
QSGVKVEAQC KVELRGNGIY DNRGHGIITK GDSTIVIEND IIGNRGSGLQ LLPRSDTKVI
KNRIHSFRAY GIAVRGRAKA LVQENIIFQG KTSKTIFQQI SNNRECIMQN NKFLVFKKKS
DTWRLVNPPA RPHLENSLRR PSAAHNGQKV TAMATRITAR VEGGYHSNRS VFCTIL

Domain Architecture (From InterPro) ▾

The same domains may appear in multiple rows, following InterPro convention.

Start	End	Type	Name	InterPro	Source
1	48	Domain	F-box domain	IPR001810	PS50181
6	48	Domain	F-box domain	IPR001810	SM00256
6	80	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
6	50	Domain	F-box domain	IPR001810	PF12937
108	254	Homologous_superfamily	Pectin lyase fold/virulence factor	IPR011050	SSF51126
198	217	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
238	260	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
341	515	Domain	Carbohydrate-binding/sugar hydrolysis domain	IPR006633	SM00722
414	587	Homologous_superfamily	Pectin lyase fold	IPR012334	G3DSA:2.160.20.10
425	572	Domain	Right handed beta helix domain	IPR039448	PF13229
425	573	Homologous_superfamily	Pectin lyase fold/virulence factor	IPR011050	SSF51126
427	448	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
449	470	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
471	493	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
494	516	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
517	539	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
534	573	Repeat	Parallel beta-helix repeat-2	IPR022441	TIGR03804
540	676	Domain	Carbohydrate-binding/sugar hydrolysis domain	IPR006633	SM00722
540	562	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
542	678	Homologous_superfamily	Pectin lyase fold/virulence factor	IPR011050	SSF51126
563	585	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
586	608	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
588	716	Homologous_superfamily	Pectin lyase fold	IPR012334	G3DSA:2.160.20.10
609	631	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
632	654	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
655	677	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
685	810	Domain	Carbohydrate-binding/sugar hydrolysis domain	IPR006633	SM00722
717	902	Homologous_superfamily	Pectin lyase fold	IPR012334	G3DSA:2.160.20.10
719	741	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
724	870	Domain	Periplasmic copper-binding protein NosD, beta helix domain	IPR007742	PF05048
727	893	Homologous_superfamily	Pectin lyase fold/virulence factor	IPR011050	SSF51126
742	764	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
766	788	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
789	811	Repeat	Parallel beta-helix repeat	IPR006626	SM00710
834	856	Repeat	Parallel beta-helix repeat	IPR006626	SM00710

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0006915	apoptotic process	Biological Process	IEA	GO_REF:0000043
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0042981	regulation of apoptotic process	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8952618
GO:0000151	ubiquitin ligase complex	Cellular Component	NAS	PMID:10531035
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	NAS	PMID:10531035
GO:0005515	protein binding	Molecular Function	IPI	PMID:23431138

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