TRI10

Details:

UniProt Entry: Q9UDY6
Gene: TRIM10
Class: RING
Family: RING5
Protein length: 481
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link
PDB Structures: 7qs0

Protein Sequence ▾

>Q9UDY6
MASAASVTSL ADEVNCPICQ GTLREPVTID CGHNFCRACL TRYCEIPGPD LEESPTCPLC
KEPFRPGSFR PNWQLANVVE NIERLQLVST LGLGEEDVCQ EHGEKIYFFC EDDEMQLCVV
CREAGEHATH TMRFLEDAAA PYREQIHKCL KCLRKEREEI QEIQSRENKR MQVLLTQVST
KRQQVISEFA HLRKFLEEQQ SILLAQLESQ DGDILRQRDE FDLLVAGEIC RFSALIEELE
EKNERPAREL LTDIRSTLIR CETRKCRKPV AVSPELGQRI RDFPQQALPL QREMKMFLEK
LCFELDYEPA HISLDPQTSH PKLLLSEDHQ RAQFSYKWQN SPDNPQRFDR ATCVLAHTGI
TGGRHTWVVS IDLAHGGSCT VGVVSEDVQR KGELRLRPEE GVWAVRLAWG FVSALGSFPT
RLTLKEQPRQ VRVSLDYEVG WVTFTNAVTR EPIYTFTASF TRKVIPFFGL WGRGSSFSLS
S

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
2	91	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
13	61	Domain	TRIM10, RING-HC finger	IPR042784	cd16593
16	60	Domain	Zinc finger, RING-type	IPR001841	SM00184
16	61	Domain	Zinc finger, RING-type	IPR001841	PS50089
31	40	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
94	135	Domain	B-box-type zinc finger	IPR000315	SM00336
94	135	Domain	B-box-type zinc finger	IPR000315	PS50119
95	132	Domain	B-box-type zinc finger	IPR000315	PF00643
290	481	Homologous_superfamily	B30.2/SPRY domain superfamily	IPR043136	G3DSA:2.60.120.920
292	481	Domain	B30.2/SPRY domain	IPR001870	PS50188
308	475	Homologous_superfamily	Concanavalin A-like lectin/glucanase domain superfamily	IPR013320	SSF49899
308	325	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
309	361	Domain	SPRY-associated	IPR006574	SM00589
313	359	Domain	SPRY-associated	IPR006574	PF13765
325	342	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
347	371	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
362	480	Domain	SPRY domain	IPR003877	SM00449
364	477	Domain	SPRY domain	IPR003877	PF00622
379	392	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
422	446	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
452	470	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0030218	erythrocyte differentiation	Biological Process	IEA	GO_REF:0000107
GO:0045087	innate immune response	Biological Process	IBA	GO_REF:0000033
GO:0046597	host-mediated suppression of symbiont invasion	Biological Process	IEA	GO_REF:0000107
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:25416956
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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