ANFY1

Protein Sequence ▾

Domain Architecture (From InterPro) ▾

The same domains may appear in multiple rows, following InterPro convention.

Start	End	Type	Name	InterPro	Source
36	193	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
48	157	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
60	156	Domain	BTB/POZ domain	IPR000210	PF00651
68	162	Domain	BTB/POZ domain	IPR000210	SM00225
68	130	Domain	BTB/POZ domain	IPR000210	PS50097
194	344	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
221	521	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	SSF48403
255	284	Repeat	Ankyrin repeat	IPR002110	SM00248
268	309	Repeat	Ankyrin repeat	IPR002110	PF13637
288	317	Repeat	Ankyrin repeat	IPR002110	SM00248
322	362	Repeat	Ankyrin repeat	IPR002110	SM00248
322	365	Repeat	Ankyrin repeat	IPR002110	PS50088
325	364	Repeat	Ankyrin repeat	IPR002110	PF00023
345	532	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
366	396	Repeat	Ankyrin repeat	IPR002110	SM00248
366	399	Repeat	Ankyrin repeat	IPR002110	PS50088
400	452	Repeat	Ankyrin repeat	IPR002110	SM00248
449	713	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	SSF48403
477	524	Repeat	Ankyrin repeat	IPR002110	PF13857
490	522	Repeat	Ankyrin repeat	IPR002110	PS50088
490	519	Repeat	Ankyrin repeat	IPR002110	SM00248
491	506	Repeat	Ankyrin repeat	IPR002110	PR01415
533	717	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
542	574	Repeat	Ankyrin repeat	IPR002110	PS50088
542	572	Repeat	Ankyrin repeat	IPR002110	SM00248
544	575	Repeat	Ankyrin repeat	IPR002110	PF00023
588	617	Repeat	Ankyrin repeat	IPR002110	SM00248
598	684	Repeat	Ankyrin repeat	IPR002110	PF12796
621	653	Repeat	Ankyrin repeat	IPR002110	PS50088
621	650	Repeat	Ankyrin repeat	IPR002110	SM00248
654	686	Repeat	Ankyrin repeat	IPR002110	PS50088
654	683	Repeat	Ankyrin repeat	IPR002110	SM00248
687	716	Repeat	Ankyrin repeat	IPR002110	SM00248
723	862	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
724	753	Repeat	Ankyrin repeat	IPR002110	SM00248
727	1079	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	SSF48403
729	834	Repeat	Ankyrin repeat	IPR002110	PF12796
769	801	Repeat	Ankyrin repeat	IPR002110	PS50088
769	798	Repeat	Ankyrin repeat	IPR002110	SM00248
785	799	Repeat	Ankyrin repeat	IPR002110	PR01415
802	830	Repeat	Ankyrin repeat	IPR002110	SM00248
836	865	Repeat	Ankyrin repeat	IPR002110	SM00248
863	944	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
870	902	Repeat	Ankyrin repeat	IPR002110	PS50088
870	899	Repeat	Ankyrin repeat	IPR002110	SM00248
905	937	Repeat	Ankyrin repeat	IPR002110	PS50088
905	934	Repeat	Ankyrin repeat	IPR002110	SM00248
910	999	Repeat	Ankyrin repeat	IPR002110	PF12796
938	970	Repeat	Ankyrin repeat	IPR002110	PS50088
938	967	Repeat	Ankyrin repeat	IPR002110	SM00248
945	1100	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
971	1001	Repeat	Ankyrin repeat	IPR002110	SM00248
971	992	Repeat	Ankyrin repeat	IPR002110	PS50088
1005	1039	Repeat	Ankyrin repeat	IPR002110	SM00248
1043	1074	Repeat	Ankyrin repeat	IPR002110	SM00248
1043	1075	Repeat	Ankyrin repeat	IPR002110	PS50088
1099	1165	Domain	FYVE zinc finger	IPR000306	SM00064
1101	1165	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
1104	1164	Domain	Zinc finger, FYVE-related	IPR017455	PS50178
1104	1163	Homologous_superfamily	Zinc finger, FYVE/PHD-type	IPR011011	SSF57903
1108	1163	Domain	FYVE zinc finger	IPR000306	PF01363

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006897	endocytosis	Biological Process	IEA	GO_REF:0000043
GO:0016197	endosomal transport	Biological Process	IMP	PMID:24102721
GO:0034058	endosomal vesicle fusion	Biological Process	IDA	PMID:15328530
GO:0042147	retrograde transport, endosome to Golgi	Biological Process	IBA	GO_REF:0000033
GO:0048549	positive regulation of pinocytosis	Biological Process	IDA	PMID:15328530
GO:0090160	Golgi to lysosome transport	Biological Process	IBA	GO_REF:0000033
GO:0030904	retromer complex	Cellular Component	IDA	PMID:22284051
GO:0010008	endosome membrane	Cellular Component	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005765	lysosomal membrane	Cellular Component	HDA	PMID:17897319
GO:0005768	endosome	Cellular Component	IDA	GO_REF:0000052
GO:0005769	early endosome	Cellular Component	IEA	GO_REF:0000044
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000120
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000120
GO:0044354	macropinosome	Cellular Component	IDA	PMID:15328530
GO:0070062	extracellular exosome	Cellular Component	HDA	PMID:18570454
GO:0005515	protein binding	Molecular Function	IPI	PMID:15328530
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0031267	small GTPase binding	Molecular Function	IBA	GO_REF:0000033
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000120
GO:1901981	phosphatidylinositol phosphate binding	Molecular Function	IDA	PMID:15328530

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If you use or refer to the Database in your publications, reports, or presentations, you must cite the paper: Dutta et al. (2025, preprint)

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For inquiries, permissions, or support regarding the Database, please contact: Dr. Ramachandra M. Bhaskara, Goethe University Frankfurt.
Email: bhaskara@med.uni-frankfurt.de.
Website maintained by Alberto Cristiani, Arghya Dutta, and Siddhanta V. Nikte.

ANFY1

Details:

Protein Sequence ▾

Domain Architecture (From InterPro) ▾

Protein functions ▾