KLHL9

Details:

UniProt Entry: Q9P2J3
Gene: KLHL9
Class: Other E3 Components
Family: Adaptor
Protein length: 617
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9P2J3
MKVSLGNGEM GVSAHLQPCK AGTTRFFTSN THSSVVLQGF DQLRIEGLLC DVTLVPGDGD
EIFPVHRAMM ASASDYFKAM FTGGMKEQDL MCIKLHGVNK VGLKKIIDFI YTAKLSLNMD
NLQDTLEAAS FLQILPVLDF CKVFLISGVS LDNCVEVGRI ANTYNLIEVD KYVNNFILKN
FPALLSTGEF LKLPFERLAF VLSSNSLKHC TELELFKAAC RWLRLEDPRM DYAAKLMKNI
RFPLMTPQDL INYVQTVDFM RTDNTCVNLL LEASNYQMMP YMQPVMQSDR TAIRSDSTHL
VTLGGVLRQQ LVVSKELRMY DERAQEWRSL APMDAPRYQH GIAVIGNFLY VVGGQSNYDT
KGKTAVDTVF RFDPRYNKWM QVASLNEKRT FFHLSALKGH LYAVGGRSAA GELATVECYN
PRMNEWSYVA KMSEPHYGHA GTVYGGLMYI SGGITHDTFQ NELMCFDPDT DKWMQKAPMT
TVRGLHCMCT VGDKLYVIGG NHFRGTSDYD DVLSCEYYSP TLDQWTPIAA MLRGQSDVGV
AVFENKIYVV GGYSWNNRCM VEIVQKYDPE KDEWHKVFDL PESLGGIRAC TLTVFPPEEN
PGSPSRESPL SAPSDHS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
6	600	Family	BTB-kelch protein	IPR017096	PIRSF037037
21	177	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
27	147	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
40	146	Domain	BTB/POZ domain	IPR000210	PF00651
50	119	Domain	BTB/POZ domain	IPR000210	PS50097
50	149	Domain	BTB/POZ domain	IPR000210	SM00225
154	255	Domain	BTB/Kelch-associated	IPR011705	SM00875
154	255	Domain	BTB/Kelch-associated	IPR011705	PF07707
284	595	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
299	591	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
299	347	Repeat	Kelch repeat type 1	IPR006652	SM00612
336	386	Repeat	Kelch repeat type 1	IPR006652	PF01344
348	399	Repeat	Kelch repeat type 1	IPR006652	SM00612
389	433	Repeat	Kelch repeat type 1	IPR006652	PF01344
400	446	Repeat	Kelch repeat type 1	IPR006652	SM00612
437	479	Repeat	Kelch repeat type 1	IPR006652	PF01344
447	493	Repeat	Kelch repeat type 1	IPR006652	SM00612
483	531	Repeat	Kelch repeat type 1	IPR006652	PF01344
494	545	Repeat	Kelch repeat type 1	IPR006652	SM00612
537	577	Repeat	Kelch repeat type 1	IPR006652	PF01344
546	594	Repeat	Kelch repeat type 1	IPR006652	SM00612

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000117
GO:0032465	regulation of cytokinesis	Biological Process	IEA	GO_REF:0000117
GO:0051301	cell division	Biological Process	IEA	GO_REF:0000043
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000117
GO:0031463	Cul3-RING ubiquitin ligase complex	Cellular Component	IEA	GO_REF:0000117
GO:0030496	midbody	Cellular Component	IDA	PMID:19995937
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:17543862
GO:0097602	cullin family protein binding	Molecular Function	IBA	GO_REF:0000033

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