KLH14

Details:

UniProt Entry: Q9P2G3
Gene: KLHL14
Class: Other E3 Components
Family: Adaptor
Protein length: 628
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9P2G3
MSRSGDRTST FDPSHSDNLL HGLNLLWRKQ LFCDVTLTAQ GQQFHCHKAV LASCSQYFRS
LFSSHPPLGG GVGGQDGLGA PKDQQQPPQQ QPSQQQQPPP QEEPGTPSSS PDDKLLTSPR
AINNLVLQGC SSIGLRLVLE YLYTANVTLS LDTVEEVLSV SKILHIPQVT KLCVQFLNDQ
ISVQNYKQVC KIAALHGLEE TKKLANKYLV EDVLLLNFEE MRALLDSLPP PVESELALFQ
MSVLWLEHDR ETRMQYAPDL MKRLRFALIP APELVERVQS VDFMRTDPVC QKLLLDAMNY
HLMPFRQHCR QSLASRIRSN KKMLLLVGGL PPGPDRLPSN LVQYYDDEKK TWKILTIMPY
NSAHHCVVEV ENFLFVLGGE DQWNPNGKHS TNFVSRYDPR FNSWIQLPPM QERRASFYAC
RLDKHLYVIG GRNETGYLSS VECYNLETNE WRYVSSLPQP LAAHAGAVHN GKIYISGGVH
NGEYVPWLYC YDPVMDVWAR KQDMNTKRAI HTLAVMNDRL YAIGGNHLKG FSHLDVMLVE
CYDPKGDQWN ILQTPILEGR SGPGCAVLDD SIYLVGGYSW SMGAYKSSTI CYCPEKGTWT
ELEGDVAEPL AGPACVTVIL PSCVPYNK

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	66	Family	BTB-kelch protein	IPR017096	PIRSF037037
1	188	Domain	Kelch-like protein 14, BTB/POZ domain	IPR030584	cd18243
8	181	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
15	202	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
24	65	Domain	BTB/POZ domain	IPR000210	PF00651
33	181	Domain	BTB/POZ domain	IPR000210	SM00225
33	151	Domain	BTB/POZ domain	IPR000210	PS50097
114	624	Family	BTB-kelch protein	IPR017096	PIRSF037037
123	180	Domain	BTB/POZ domain	IPR000210	PF00651
181	282	Domain	Kelch-like protein 14, BACK domain	IPR047027	cd18453
189	279	Domain	BTB/Kelch-associated	IPR011705	SM00875
211	279	Domain	BTB/Kelch-associated	IPR011705	PF07707
310	533	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
322	616	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
323	372	Repeat	Kelch repeat type 1	IPR006652	SM00612
363	411	Repeat	Kelch repeat type 1	IPR006652	PF01344
373	424	Repeat	Kelch repeat type 1	IPR006652	SM00612
414	458	Repeat	Kelch repeat type 1	IPR006652	PF01344
425	471	Repeat	Kelch repeat type 1	IPR006652	SM00612
461	505	Repeat	Kelch repeat type 1	IPR006652	PF01344
472	518	Repeat	Kelch repeat type 1	IPR006652	SM00612
519	570	Repeat	Kelch repeat type 1	IPR006652	SM00612
534	622	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
560	602	Repeat	Kelch repeat type 1	IPR006652	PF01344
571	620	Repeat	Kelch repeat type 1	IPR006652	SM00612

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0005783	endoplasmic reticulum	Cellular Component	IBA	GO_REF:0000033
GO:0043005	neuron projection	Cellular Component	IBA	GO_REF:0000033
GO:0043025	neuronal cell body	Cellular Component	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000043
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IEA	GO_REF:0000044
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000044
GO:0015629	actin cytoskeleton	Cellular Component	IDA	GO_REF:0000052
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0016235	aggresome	Cellular Component	IDA	GO_REF:0000052

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