WSB2

Details:

UniProt Entry: Q9NYS7
Gene: WSB2
Class: Other E3 Components
Family: Receptor
Protein length: 404
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9NYS7
MEAGEEPLLL AELKPGRPHQ FDWKSSCETW SVAFSPDGSW FAWSQGHCIV KLIPWPLEEQ
FIPKGFEAKS RSSKNETKGR GSPKEKTLDC GQIVWGLAFS PWPSPPSRKL WARHHPQVPD
VSCLVLATGL NDGQIKIWEV QTGLLLLNLS GHQDVVRDLS FTPSGSLILV SASRDKTLRI
WDLNKHGKQI QVLSGHLQWV YCCSISPDCS MLCSAAGEKS VFLWSMRSYT LIRKLEGHQS
SVVSCDFSPD SALLVTASYD TNVIMWDPYT GERLRSLHHT QVDPAMDDSD VHISSLRSVC
FSPEGLYLAT VADDRLLRIW ALELKTPIAF APMTNGLCCT FFPHGGVIAT GTRDGHVQFW
TAPRVLSSLK HLCRKALRSF LTTYQVLALP IPKKMKEFLT YRTF

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
24	186	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	IPR015943	G3DSA:2.130.10.10
26	360	Homologous_superfamily	WD40-repeat-containing domain superfamily	IPR036322	SSF50978
81	139	Repeat	WD40 repeat	IPR001680	SM00320
126	148	Repeat	WD40 repeat	IPR001680	PS50082
126	140	Repeat	G-protein beta WD-40 repeat	IPR020472	PR00320
142	182	Repeat	WD40 repeat	IPR001680	SM00320
146	182	Repeat	WD40 repeat	IPR001680	PF00400
149	184	Repeat	WD40 repeat	IPR001680	PS50082
169	183	Repeat	G-protein beta WD-40 repeat	IPR020472	PR00320
169	183	Conserved_site	WD40 repeat, conserved site	IPR019775	PS00678
186	225	Repeat	WD40 repeat	IPR001680	SM00320
187	225	Repeat	WD40 repeat	IPR001680	PF00400
187	285	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	IPR015943	G3DSA:2.130.10.10
193	234	Repeat	WD40 repeat	IPR001680	PS50082
228	267	Repeat	WD40 repeat	IPR001680	SM00320
231	267	Repeat	WD40 repeat	IPR001680	PF00400
235	276	Repeat	WD40 repeat	IPR001680	PS50082
254	268	Repeat	G-protein beta WD-40 repeat	IPR020472	PR00320
270	321	Repeat	WD40 repeat	IPR001680	SM00320
286	370	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	IPR015943	G3DSA:2.130.10.10
289	323	Repeat	WD40 repeat	IPR001680	PS50082
292	320	Repeat	WD40 repeat	IPR001680	PF00400
324	361	Repeat	WD40 repeat	IPR001680	SM00320
338	360	Repeat	WD40 repeat	IPR001680	PF00400
357	403	Homologous_superfamily	SOCS box-like domain superfamily	IPR036036	SSF158235
360	403	Domain	SOCS box domain	IPR001496	SM00253
366	402	Domain	SOCS box domain	IPR001496	SM00969
368	400	Domain	SOCS box domain	IPR001496	PF07525
368	404	Domain	SOCS box domain	IPR001496	PS50225

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0035556	intracellular signal transduction	Biological Process	IEA	GO_REF:0000002
GO:0000209	protein polyubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8952039
GO:0005515	protein binding	Molecular Function	IPI	PMID:25036637

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