KCND1

Details:

UniProt Entry: Q9NSA2
Gene: KCND1
Class: Other E3 Components
Family: Adaptor
Protein length: 647
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9NSA2
MAAGLATWLP FARAAAVGWL PLAQQPLPPA PGVKASRGDE VLVVNVSGRR FETWKNTLDR
YPDTLLGSSE KEFFYDADSG EYFFDRDPDM FRHVLNFYRT GRLHCPRQEC IQAFDEELAF
YGLVPELVGD CCLEEYRDRK KENAERLAED EEAEQAGDGP ALPAGSSLRQ RLWRAFENPH
TSTAALVFYY VTGFFIAVSV IANVVETIPC RGSARRSSRE QPCGERFPQA FFCMDTACVL
IFTGEYLLRL FAAPSRCRFL RSVMSLIDVV AILPYYIGLL VPKNDDVSGA FVTLRVFRVF
RIFKFSRHSQ GLRILGYTLK SCASELGFLL FSLTMAIIIF ATVMFYAEKG TNKTNFTSIP
AAFWYTIVTM TTLGYGDMVP STIAGKIFGS ICSLSGVLVI ALPVPVIVSN FSRIYHQNQR
ADKRRAQQKV RLARIRLAKS GTTNAFLQYK QNGGLEDSGS GEEQALCVRN RSAFEQQHHH
LLHCLEKTTC HEFTDELTFS EALGAVSPGG RTSRSTSVSS QPVGPGSLLS SCCPRRAKRR
AIRLANSTAS VSRGSMQELD MLAGLRRSHA PQSRSSLNAK PHDSLDLNCD SRDFVAAIIS
IPTPPANTPD ESQPSSPGGG GRAGSTLRNS SLGTPCLFPE TVKISSL

Domain Architecture (From InterPro) ▾

The same domains may appear in multiple rows, following InterPro convention.

Start	End	Type	Name	InterPro	Source
1	143	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
3	31	Domain	Shal-type voltage-gated potassium channels, N-terminal	IPR021645	PF11601
39	144	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
40	139	Domain	BTB/POZ domain	IPR000210	SM00225
43	131	Domain	Potassium channel tetramerisation-type BTB domain	IPR003131	PF02214
67	80	Family	Potassium channel, voltage dependent, Kv4	IPR003975	PR01497
74	83	Family	Potassium channel, voltage dependent, Kv4.1	IPR004054	PR01516
81	91	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491
142	158	Family	Potassium channel, voltage dependent, Kv4	IPR003975	PR01497
149	160	Family	Potassium channel, voltage dependent, Kv4.1	IPR004054	PR01516
162	176	Family	Potassium channel, voltage dependent, Kv4	IPR003975	PR01497
162	308	Homologous_superfamily	Voltage-dependent channel domain superfamily	IPR027359	G3DSA:1.20.120.350
181	195	Family	Potassium channel, voltage dependent, Kv4	IPR003975	PR01497
187	418	Domain	Ion transport domain	IPR005821	PF00520
222	238	Family	Potassium channel, voltage dependent, Kv4	IPR003975	PR01497
301	309	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491
320	339	Family	Potassium channel, voltage dependent, Kv4	IPR003975	PR01497
325	339	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491
396	407	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491
417	428	Family	Potassium channel, voltage dependent, Kv4	IPR003975	PR01497
431	447	Family	Potassium channel, voltage dependent, Kv4	IPR003975	PR01497
448	459	Family	Potassium channel, voltage dependent, Kv4.1	IPR004054	PR01516
461	477	Family	Potassium channel, voltage dependent, Kv4.1	IPR004054	PR01516
471	549	Domain	Potassium channel, voltage dependent, Kv4, C-terminal	IPR024587	PF11879
475	489	Family	Potassium channel, voltage dependent, Kv4	IPR003975	PR01497
554	566	Family	Potassium channel, voltage dependent, Kv4.1	IPR004054	PR01516
581	594	Family	Potassium channel, voltage dependent, Kv4.1	IPR004054	PR01516
613	624	Family	Potassium channel, voltage dependent, Kv4.1	IPR004054	PR01516
633	647	Family	Potassium channel, voltage dependent, Kv4.1	IPR004054	PR01516

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006813	potassium ion transport	Biological Process	IEA	GO_REF:0000002
GO:0071805	potassium ion transmembrane transport	Biological Process	IEA	GO_REF:0000108
GO:0001508	action potential	Biological Process	IBA	GO_REF:0000033
GO:0006811	monoatomic ion transport	Biological Process	IEA	GO_REF:0000120
GO:0034220	monoatomic ion transmembrane transport	Biological Process	IEA	GO_REF:0000043
GO:0051260	protein homooligomerization	Biological Process	IEA	GO_REF:0000002
GO:0055085	transmembrane transport	Biological Process	IEA	GO_REF:0000002
GO:0008076	voltage-gated potassium channel complex	Cellular Component	IEA	GO_REF:0000002
GO:0043025	neuronal cell body	Cellular Component	IBA	GO_REF:0000033
GO:0043197	dendritic spine	Cellular Component	IBA	GO_REF:0000033
GO:0045211	postsynaptic membrane	Cellular Component	IBA	GO_REF:0000033
GO:0005886	plasma membrane	Cellular Component	IEA	GO_REF:0000120
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000120
GO:0034702	monoatomic ion channel complex	Cellular Component	IEA	GO_REF:0000043
GO:0005249	voltage-gated potassium channel activity	Molecular Function	IEA	GO_REF:0000002
GO:0005216	monoatomic ion channel activity	Molecular Function	IEA	GO_REF:0000002
GO:0005250	A-type (transient outward) potassium channel activity	Molecular Function	IBA	GO_REF:0000033
GO:0005267	potassium channel activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043

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