FBX8

Details:

UniProt Entry: Q9NRD0
Gene: FBXO8
Class: Other E3 Components
Family: Receptor
Protein length: 319
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9NRD0
MGQGLWRVVR NQQLQQEGYS EQGYLTREQS RRMAASNISN TNHRKQVQGG IDIYHLLKAR
KSKEQEGFIN LEMLPPELSF TILSYLNATD LCLASCVWQD LANDELLWQG LCKSTWGHCS
IYNKNPPLGF SFRKLYMQLD EGSLTFNANP DEGVNYFMSK GILDDSPKEI AKFIFCTRTL
NWKKLRIYLD ERRDVLDDLV TLHNFRNQFL PNALREFFRH IHAPEERGEY LETLITKFSH
RFCACNPDLM RELGLSPDAV YVLCYSLILL SIDLTSPHVK NKMSKREFIR NTRRAAQNIS
EDFVGHLYDN IYLIGHVAA

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
61	139	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
68	111	Domain	F-box domain	IPR001810	PS50181
74	112	Domain	F-box domain	IPR001810	PF12937
132	316	Domain	Sec7 domain	IPR000904	SM00222
133	314	Domain	Sec7 domain	IPR000904	PS50190
133	312	Domain	Sec7 domain	IPR000904	cd00171
136	312	Homologous_superfamily	Sec7 domain superfamily	IPR035999	SSF48425
139	311	Domain	Sec7 domain	IPR000904	PF01369
207	314	Homologous_superfamily	Sec7, C-terminal domain superfamily	IPR023394	G3DSA:1.10.1000.11

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IEA	GO_REF:0000107
GO:0032012	regulation of ARF protein signal transduction	Biological Process	IEA	GO_REF:0000002
GO:0000151	ubiquitin ligase complex	Cellular Component	IEA	GO_REF:0000107
GO:0005515	protein binding	Molecular Function	IPI	PMID:26871637
GO:0005085	guanyl-nucleotide exchange factor activity	Molecular Function	IEA	GO_REF:0000120

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