ZBT26

Details:

UniProt Entry: Q9HCK0
Gene: ZBTB26
Class: RING
Family: RING6
Protein length: 441
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>Q9HCK0
MSERSDLLHF KFENYGDSML QKMNKLREEN KFCDVTVLID DIEVQGHKIV FAAGSPFLRD
QFLLNDSREV KISILQSSEV GRQLLLSCYS GVLEFPEMEL VNYLTAASFL QMSHIVERCT
QALWKFIKPK QPMDSKEGCE PQSASPQSKE QQGDARGSPK QDSPCIHPSE DSMDMEDSDI
QIVKVESIGD VSEVRSKKDQ NQFISSEPTA LHSSEPQHSL INSTVENRVS EIEQNHLHNY
ALSYTGSDNI IMASKDVFGP NIRGVDKGLQ WHHQCPKCTR VFRHLENYAN HLKMHKLFMC
LLCGKTFTQK GNLHRHMRVH AGIKPFQCKI CGKTFSQKCS LQDHLNLHSG DKPHKCNYCD
MVFAHKPVLR KHLKQLHGKN SFDNANERNV QDLTVDFDSF ACTTVTDSKG CQPQPDATQV
LDAGKLAQAV LNLRNDSTCV N

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
6	126	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
7	156	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
23	123	Domain	BTB/POZ domain	IPR000210	PF00651
33	127	Domain	BTB/POZ domain	IPR000210	SM00225
33	97	Domain	BTB/POZ domain	IPR000210	PS50097
273	295	Domain	Zinc finger C2H2-type	IPR013087	PS50157
273	295	Domain	Zinc finger C2H2-type	IPR013087	PF00096
273	295	Domain	Zinc finger C2H2-type	IPR013087	SM00355
296	344	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
298	325	Domain	Zinc finger C2H2-type	IPR013087	PS50157
298	320	Domain	Zinc finger C2H2-type	IPR013087	SM00355
298	320	Domain	Zinc finger C2H2-type	IPR013087	PF00096
300	320	Domain	Zinc finger C2H2-type	IPR013087	PS00028
326	348	Domain	Zinc finger C2H2-type	IPR013087	SM00355
326	353	Domain	Zinc finger C2H2-type	IPR013087	PS50157
326	348	Domain	Zinc finger C2H2-type	IPR013087	PF00096
328	348	Domain	Zinc finger C2H2-type	IPR013087	PS00028
334	378	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
354	377	Domain	Zinc finger C2H2-type	IPR013087	PF00096
354	377	Domain	Zinc finger C2H2-type	IPR013087	SM00355
354	377	Domain	Zinc finger C2H2-type	IPR013087	PS50157
356	377	Domain	Zinc finger C2H2-type	IPR013087	PS00028

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0000122	negative regulation of transcription by RNA polymerase II	Biological Process	IBA	GO_REF:0000033
GO:0001817	regulation of cytokine production	Biological Process	IBA	GO_REF:0000033
GO:0002682	regulation of immune system process	Biological Process	IBA	GO_REF:0000033
GO:0005654	nucleoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Molecular Function	IBA	GO_REF:0000033
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Molecular Function	IBA	GO_REF:0000033
GO:0003677	DNA binding	Molecular Function	IEA	GO_REF:0000120
GO:0005515	protein binding	Molecular Function	IPI	PMID:25416956
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0042802	identical protein binding	Molecular Function	IPI	PMID:25416956
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:1990837	sequence-specific double-stranded DNA binding	Molecular Function	IDA	PMID:28473536

Enzyme–Substrate Interactions ▾

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