RN122

Details:

UniProt Entry: Q9H9V4
Gene: RNF122
Class: RING
Family: RING4
Protein length: 155
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q9H9V4
MHPFQWCNGC FCGLGLVSTN KSCSMPPISF QDLPLNIYMV IFGTGIFVFM LSLIFCCYFI
SKLRNQAQSE RYGYKEVVLK GDAKKLQLYG QTCAVCLEDF KGKDELGVLP CQHAFHRKCL
VKWLEVRCVC PMCNKPIASP SEATQNIGIL LDELV

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
80	149	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
92	134	Domain	Zinc finger, RING-type	IPR001841	PF13639
93	134	Domain	Zinc finger, RING-type	IPR001841	PS50089
93	133	Domain	Zinc finger, RING-type	IPR001841	SM00184

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0010917	negative regulation of mitochondrial membrane potential	Biological Process	IDA	PMID:16751333
GO:0043065	positive regulation of apoptotic process	Biological Process	IDA	PMID:16751333
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IMP	PMID:20553626
GO:0051865	protein autoubiquitination	Biological Process	IMP	PMID:20553626
GO:0005737	cytoplasm	Cellular Component	IDA	PMID:20553626
GO:0005783	endoplasmic reticulum	Cellular Component	IEA	GO_REF:0000120
GO:0005794	Golgi apparatus	Cellular Component	IEA	GO_REF:0000120
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000120
GO:0005515	protein binding	Molecular Function	IPI	PMID:20553626
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IMP	PMID:20553626

Enzyme–Substrate Interactions ▾

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