KLH31

Details:

UniProt Entry: Q9H511
Gene: KLHL31
Class: Other E3 Components
Family: Adaptor
Protein length: 634
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9H511
MAPKKKIVKK NKGDINEMTI IVEDSPLNKL NALNGLLEGG NGLSCISSEL TDASYGPNLL
EGLSKMRQEN FLCDLVIGTK TKSFDVHKSV MASCSEYFYN ILKKDPSIQR VDLNDISPLG
LATVIAYAYT GKLTLSLYTI GSIISAAVYL QIHTLVKMCS DFLIREMSVE NCMYVVNIAE
TYSLKNAKAA AQKFIRDNFL EFAESDQFMK LTFEQINELL IDDDLQLPSE IVAFQIAMKW
LEFDQKRVKY AADLLSNIRF GTISAQDLVN YVQSVPRMMQ DADCHRLLVD AMNYHLLPYH
QNTLQSRRTR IRGGCRVLVT VGGRPGLTEK SLSRDILYRD PENGWSKLTE MPAKSFNQCV
AVMDGFLYVA GGEDQNDARN QAKHAVSNFC RYDPRFNTWI HLASMNQKRT HFSLSVFNGL
VYAAGGRNAE GSLASLECYV PSTNQWQPKT PLEVARCCHA SAVADGRVLV TGGYIANAYS
RSVCAYDPAS DSWQELPNLS TPRGWHCAVT LSDRVYVMGG SQLGPRGERV DVLTVECYSP
ATGQWSYAAP LQVGVSTAGV SALHGRAYLV GGWNEGEKKY KKCIQCFSPE LNEWTEDDEL
PEATVGVSCC TLSMPNNVTR ESRASSVSSV PVSI

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
45	619	Family	BTB-kelch protein	IPR017096	PIRSF037037
51	165	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
51	195	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
55	174	Domain	Kelch-like protein 31, BTB/POZ domain	IPR030604	cd18260
64	165	Domain	BTB/POZ domain	IPR000210	PF00651
73	167	Domain	BTB/POZ domain	IPR000210	SM00225
73	137	Domain	BTB/POZ domain	IPR000210	PS50097
172	273	Domain	BTB/Kelch-associated	IPR011705	SM00875
172	273	Domain	BTB/Kelch-associated	IPR011705	PF07707
301	627	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
317	365	Repeat	Kelch repeat type 1	IPR006652	SM00612
318	611	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
366	419	Repeat	Kelch repeat type 1	IPR006652	SM00612
409	452	Repeat	Kelch repeat type 1	IPR006652	PF01344
420	466	Repeat	Kelch repeat type 1	IPR006652	SM00612
455	500	Repeat	Kelch repeat type 1	IPR006652	PF01344
467	513	Repeat	Kelch repeat type 1	IPR006652	SM00612
506	551	Repeat	Kelch repeat type 1	IPR006652	PF01344
514	565	Repeat	Kelch repeat type 1	IPR006652	SM00612
558	596	Repeat	Kelch repeat type 1	IPR006652	PF01344
566	614	Repeat	Kelch repeat type 1	IPR006652	SM00612

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0001933	negative regulation of protein phosphorylation	Biological Process	IMP	PMID:18719355
GO:0046329	negative regulation of JNK cascade	Biological Process	IBA	GO_REF:0000033
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033

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