FBX44

Details:

UniProt Entry: Q9H4M3
Gene: FBXO44
Class: Other E3 Components
Family: Receptor
Protein length: 255
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9H4M3
MAVGNINELP ENILLELFTH VPARQLLLNC RLVCSLWRDL IDLVTLWKRK CLREGFITED
WDQPVADWKI FYFLRSLHRN LLHNPCAEEG FEFWSLDVNG GDEWKVEDLS RDQRKEFPND
QVKKYFVTSY YTCLKSQVVD LKAEGYWEEL MDTTRPDIEV KDWFAARPDC GSKYQLCVQL
LSSAHAPLGT FQPDPATIQQ KSDAKWREVS HTFSNYPPGV RYIWFQHGGV DTHYWAGWYG
PRVTNSSITI GPPLP

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
3	50	Domain	F-box domain	IPR001810	PS50181
3	253	Family	F-box only protein	IPR039752	PTHR12125
4	83	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
6	53	Domain	F-box domain	IPR001810	PF12937
9	50	Domain	F-box domain	IPR001810	SM00256
68	251	Homologous_superfamily	Galactose-binding-like domain superfamily	IPR008979	SSF49785
68	252	Domain	F-box associated (FBA) domain	IPR007397	SM01198
71	252	Domain	F-box associated (FBA) domain	IPR007397	PS51114
72	250	Domain	F-box associated (FBA) domain	IPR007397	PF04300

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0010498	proteasomal protein catabolic process	Biological Process	IDA	PMID:25970626
GO:0006516	glycoprotein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0036503	ERAD pathway	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000117
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8952618
GO:0019005	SCF ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:18203720

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