FXL15

Details:

UniProt Entry: Q9H469
Gene: FBXL15
Class: Other E3 Components
Family: Receptor
Protein length: 300
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9H469
MEPPMEPSGG EQEPGAVRFL DLPWEDVLLP HVLNRVPLRQ LLRLQRVSRA FRSLVQLHLA
GLRRFDAAQV GPQIPRAALA RLLRDAEGLQ ELALAPCHEW LSDEDLVPVL ARNPQLRSVA
LGGCGQLSRR ALGALAEGCP RLQRLSLAHC DWVDGLALRG LADRCPALEE LDLTACRQLK
DEAIVYLAQR RGAGLRSLSL AVNANVGDAA VQELARNCPE LHHLDLTGCL RVGSDGVRTL
AEYCPVLRSL RVRHCHHVAE SSLSRLRKRG VDIDVEPPLH QALVLLQDMA GFAPFVNLQV

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
12	275	Homologous_superfamily	Leucine-rich repeat domain superfamily	IPR032675	G3DSA:3.80.10.10
18	56	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
19	56	Domain	F-box domain	IPR001810	PF00646
113	138	Repeat	Leucine-rich repeat, cysteine-containing subtype	IPR006553	SM00367
139	164	Repeat	Leucine-rich repeat, cysteine-containing subtype	IPR006553	SM00367
165	190	Repeat	Leucine-rich repeat, cysteine-containing subtype	IPR006553	SM00367
192	217	Repeat	Leucine-rich repeat, cysteine-containing subtype	IPR006553	SM00367
218	243	Repeat	Leucine-rich repeat, cysteine-containing subtype	IPR006553	SM00367
218	241	Repeat	Leucine-rich repeat	IPR001611	PF13516
244	269	Repeat	Leucine-rich repeat, cysteine-containing subtype	IPR006553	SM00367

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0030282	bone mineralization	Biological Process	IEA	GO_REF:0000107
GO:0000086	G2/M transition of mitotic cell cycle	Biological Process	IMP	PMID:21572392
GO:0009953	dorsal/ventral pattern formation	Biological Process	ISS	GO_REF:0000024
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0030513	positive regulation of BMP signaling pathway	Biological Process	IMP	PMID:21572392
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8952618
GO:0019005	SCF ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:21572392

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