RN208

Details:

UniProt Entry: Q9H0X6
Gene: RNF208
Class: RING
Family: RING4
Protein length: 261
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q9H0X6
MPSDPGPEAG SGWPGLLMSC LKGPHVILKM EAMKIVHPEK FPELPAAPCF PPAPRPTPTL
APKRAWPSDT EIIVNQACGG DMPALEGAPH TPPLPRRPRK GSSELGFPRV APEDEVIVNQ
YVIRPGPSAS AASSAAAGEP LECPTCGHSY NVTQRRPRVL SCLHSVCEQC LQILYESCPK
YKFISCPTCR RETVLFTDYG LAALAVNTSI LSRLPPEALT APSGGQWGAE PEGSCYQTFR
QYCGAACTCH VRNPLSACSI M

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
128	214	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
140	193	Domain	RING finger protein 208, HC type RING finger	IPR040100	cd16559
143	190	Domain	Zinc finger, RING-type	IPR001841	PS50089
162	171	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0051865	protein autoubiquitination	Biological Process	IDA	PMID:24105792
GO:0005654	nucleoplasm	Cellular Component	IDA	GO_REF:0000052
GO:0005829	cytosol	Cellular Component	IDA	GO_REF:0000052
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IDA	PMID:24105792
GO:0005515	protein binding	Molecular Function	IPI	PMID:16189514
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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