UNK

Details:

UniProt Entry: Q9C0B0
Gene: UNK
Class: RING
Family: RING7
Protein length: 810
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q9C0B0
MSKGPGPGGS AASSAPPAAT AQVLQAQPEK PQHYTYLKEF RTEQCPLFVQ HKCTQHRPYT
CFHWHFVNQR RRRSIRRRDG TFNYSPDVYC TKYDEATGLC PEGDECPFLH RTTGDTERRY
HLRYYKTGIC IHETDSKGNC TKNGLHCAFA HGPHDLRSPV YDIRELQAME ALQNGQTTVE
GSIEGQSAGA ASHAMIEKIL SEEPRWQETA YVLGNYKTEP CKKPPRLCRQ GYACPYYHNS
KDRRRSPRKH KYRSSPCPNV KHGDEWGDPG KCENGDACQY CHTRTEQQFH PEIYKSTKCN
DMQQSGSCPR GPFCAFAHVE QPPLSDDLQP SSAVSSPTQP GPVLYMPSAA GDSVPVSPSS
PHAPDLSALL CRNSSLGSPS NLCGSPPGSI RKPPNLEGIV FPGESGLAPG SYKKAPGFER
EDQVGAEYLK NFKCQAKLKP HSLEPRSQEQ PLLQPKQDML GILPAGSPLT SSISSSITSS
LAATPPSPVG TSSVPGMNAN ALPFYPTSDT VESVIESALD DLDLNEFGVA ALEKTFDNST
VPHPGSITIG GSLLQSSAPV NIPGSLGSSA SFHSASPSPP VSLSSHFLQQ PQGHLSQSEN
TFLGTSASHG SLGLNGMNSS IWEHFASGSF SPGTSPAFLS GPGAAELARL RQELDEANST
IKQWEESWKQ AKQACDAWKK EAEEAGERAS AAGAECELAR EQRDALEVQV KKLQEELERL
HAGPEPQALP AFSDLEALSL STLYSLQKQL RAHLEQVDKA VFHMQSVKCL KCQEQKRAVL
PCQHAALCEL CAEGSECPIC QPGRAHTLQS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
34	73	Domain	Unkempt, zinc finger domain 1	IPR040594	PF18384
84	113	Domain	Zinc finger, CCCH-type	IPR000571	PS50103
85	112	Domain	Zinc finger, CCCH-type	IPR000571	SM00356
116	699	Family	RING finger protein Unkempt-like	IPR045234	PTHR14493
124	153	Domain	Zinc finger, CCCH-type	IPR000571	SM00356
124	154	Domain	Zinc finger, CCCH-type	IPR000571	PS50103
215	240	Domain	Zinc finger, CCCH-type	IPR000571	SM00356
251	284	Domain	Zinc finger, CCCH-type	IPR000571	SM00356
251	285	Domain	Zinc finger, CCCH-type	IPR000571	PS50103
290	320	Homologous_superfamily	Zinc finger, CCCH-type superfamily	IPR036855	SSF90229
293	321	Domain	Zinc finger, CCCH-type	IPR000571	PS50103
293	320	Domain	Zinc finger, CCCH-type	IPR000571	SM00356
294	319	Domain	Zinc finger, CCCH-type	IPR000571	PF00642

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0001701	in utero embryonic development	Biological Process	IEA	GO_REF:0000107
GO:0001764	neuron migration	Biological Process	IEA	GO_REF:0000107
GO:0006417	regulation of translation	Biological Process	IEA	GO_REF:0000043
GO:0048667	cell morphogenesis involved in neuron differentiation	Biological Process	IBA	GO_REF:0000033
GO:2000766	negative regulation of cytoplasmic translation	Biological Process	IMP	PMID:25737280
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0003723	RNA binding	Molecular Function	IEA	GO_REF:0000043
GO:0043022	ribosome binding	Molecular Function	IEA	GO_REF:0000107
GO:1990715	mRNA CDS binding	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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