TRI55

Details:

UniProt Entry: Q9BYV6
Gene: TRIM55
Class: RING
Family: RING5
Protein length: 548
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q9BYV6
MSASLNYKSF SKEQQTMDNL EKQLICPICL EMFTKPVVIL PCQHNLCRKC ASDIFQASNP
YLPTRGGTTM ASGGRFRCPS CRHEVVLDRH GVYGLQRNLL VENIIDIYKQ ESTRPEKKSD
QPMCEEHEEE RINIYCLNCE VPTCSLCKVF GAHKDCQVAP LTHVFQRQKS ELSDGIAILV
GSNDRVQGVI SQLEDTCKTI EECCRKQKQE LCEKFDYLYG ILEERKNEMT QVITRTQEEK
LEHVRALIKK YSDHLENVSK LVESGIQFMD EPEMAVFLQN AKTLLKKISE ASKAFQMEKI
EHGYENMNHF TVNLNREEKI IREIDFYRED EDEEEEEGGE GEKEGEGEVG GEAVEVEEVE
NVQTEFPGED ENPEKASELS QVELQAAPGA LPVSSPEPPP ALPPAADAPV TQGEVVPTGS
EQTTESETPV PAAAETADPL FYPSWYKGQT RKATTNPPCT PGSEGLGQIG PPGSEDSNVR
KAEVAAAAAS ERAAVSGKET SAPAATSQIG FEAPPLQGQA AAPASGSGAD SEPARHIFSF
SWLNSLNE

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
4	119	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
26	79	Domain	Zinc finger, RING-type, eukaryotic	IPR027370	PF13445
26	82	Domain	Zinc finger, RING-type	IPR001841	PS50089
26	81	Domain	Zinc finger, RING-type	IPR001841	SM00184
42	51	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
119	161	Domain	B-box-type zinc finger	IPR000315	PS50119
119	161	Domain	B-box-type zinc finger	IPR000315	SM00336
120	163	Domain	B-box-type zinc finger	IPR000315	PF00643
269	327	Domain	COS domain	IPR017903	PS51262

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0007249	canonical NF-kappaB signal transduction	Biological Process	IDA	PMID:37816088
GO:0070534	protein K63-linked ubiquitination	Biological Process	IDA	PMID:37816088
GO:1901224	positive regulation of non-canonical NF-kappaB signal transduction	Biological Process	IDA	PMID:37816088
GO:1905517	macrophage migration	Biological Process	IEA	GO_REF:0000107
GO:0002523	leukocyte migration involved in inflammatory response	Biological Process	IEA	GO_REF:0000107
GO:0050904	diapedesis	Biological Process	IEA	GO_REF:0000107
GO:0007165	signal transduction	Biological Process	NAS	PMID:11243782
GO:0045087	innate immune response	Biological Process	IBA	GO_REF:0000033
GO:0070936	protein K48-linked ubiquitination	Biological Process	IDA	PMID:37816088
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0005874	microtubule	Cellular Component	NAS	PMID:11243782
GO:0005515	protein binding	Molecular Function	IPI	PMID:22493164
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0030674	protein-macromolecule adaptor activity	Molecular Function	IDA	PMID:37816088
GO:0042802	identical protein binding	Molecular Function	IPI	PMID:22493164
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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