TRI34

Details:

UniProt Entry: Q9BYJ4
Gene: TRIM34
Class: RING
Family: RING5
Protein length: 488
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link
PDB Structures: 2egp

Protein Sequence ▾

>Q9BYJ4
MASKILLNVQ EEVTCPICLE LLTEPLSLDC GHSLCRACIT VSNKEAVTSM GGKSSCPVCG
ISYSFEHLQA NQHLANIVER LKEVKLSPDN GKKRDLCDHH GEKLLLFCKE DRKVICWLCE
RSQEHRGHHT VLTEEVFKEC QEKLQAVLKR LKKEEEEAEK LEADIREEKT SWKYQVQTER
QRIQTEFDQL RSILNNEEQR ELQRLEEEEK KTLDKFAEAE DELVQQKQLV RELISDVECR
SQWSTMELLQ DMSGIMKWSE IWRLKKPKMV SKKLKTVFHA PDLSRMLQMF RELTAVRCYW
VDVTLNSVNL NLNLVLSEDQ RQVISVPIWP FQCYNYGVLG SQYFSSGKHY WEVDVSKKTA
WILGVYCRTY SRHMKYVVRR CANRQNLYTK YRPLFGYWVI GLQNKCKYGV FEESLSSDPE
VLTLSMAVPP CRVGVFLDYE AGIVSFFNVT SHGSLIYKFS KCCFSQPVYP YFNPWNCPAP
MTLCPPSS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	91	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
15	59	Domain	Zinc finger, RING-type	IPR001841	SM00184
15	59	Domain	Zinc finger, RING-type	IPR001841	PS50089
30	39	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
92	133	Domain	B-box-type zinc finger	IPR000315	SM00336
92	134	Domain	B-box-type zinc finger	IPR000315	PS50119
93	131	Domain	B-box-type zinc finger	IPR000315	PF00643
283	488	Domain	B30.2/SPRY domain	IPR001870	PS50188
290	488	Homologous_superfamily	B30.2/SPRY domain superfamily	IPR043136	G3DSA:2.60.120.920
295	486	Homologous_superfamily	Concanavalin A-like lectin/glucanase domain superfamily	IPR013320	SSF49899
299	316	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
300	485	Domain	TRIM34, PRY/SPRY domain	IPR035826	cd15825
346	487	Domain	SPRY domain	IPR003877	SM00449
348	473	Domain	SPRY domain	IPR003877	PF00622
424	448	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
456	474	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0010468	regulation of gene expression	Biological Process	IBA	GO_REF:0000033
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0045087	innate immune response	Biological Process	IBA	GO_REF:0000033
GO:0051607	defense response to virus	Biological Process	IEA	GO_REF:0000043
GO:0080090	regulation of primary metabolic process	Biological Process	IEA	GO_REF:0000117
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005739	mitochondrion	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-1031716
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0042802	identical protein binding	Molecular Function	IEA	GO_REF:0000117
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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