NEUL2

Details:

UniProt Entry: Q9BR09
Gene: NEURL2
Class: Other E3 Components
Family: Receptor
Protein length: 285
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q9BR09
MAAASEPVDS GALWGLERPE PPPTRFHRVH GANIRVDPSG TRATRVESFA HGVCFSREPL
APGQVFLVEI EEKELGWCGH LRLGLTALDP ASLAPVPEFS LPDLVNLGHT WVFAITRHHN
RVPREGRPEA EAAAPSRPPT LLVEPYLRIE QFRIPRDRLV GRSRPGLYSH LLDQLYELNV
LPPTARRSRL GVLFCPRPDG TADMHIIING EDMGPSARGL PAAQPLYAVV DVFASTKSVR
LVQLEYGLPS LQTLCRLVIQ RSMVHRLAID GLHLPKELKD FCKYE

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
20	243	Family	Neuralized	IPR037962	PTHR12429
21	127	Domain	Neuralized homology repeat (NHR) domain	IPR006573	SM00588
23	244	Domain	Neuralized homology repeat (NHR) domain	IPR006573	PS51065
25	243	Homologous_superfamily	B30.2/SPRY domain superfamily	IPR043136	G3DSA:2.60.120.920
26	242	Domain	Neuralized homology repeat (NHR) domain	IPR006573	PF07177
243	284	Homologous_superfamily	SOCS box-like domain superfamily	IPR036036	SSF158235
248	285	Domain	SOCS box domain	IPR001496	SM00969
249	283	Domain	SOCS box domain	IPR001496	PF07525
250	285	Domain	SOCS box domain	IPR001496	PS50225

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0035556	intracellular signal transduction	Biological Process	IEA	GO_REF:0000002
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8952039
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

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