TS101

>Q99816
MAVSESQLKK MVSKYKYRDL TVRETVNVIT LYKDLKPVLD SYVFNDGSSR ELMNLTGTIP
VPYRGNTYNI PICLWLLDTY PYNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHEWKHP
QSDLLGLIQV MIVVFGDEPP VFSRPISASY PPYQATGPPN TSYMPGMPGG ISPYPSGYPP
NPSGYPGCPY PPGGPYPATT SSQYPSQPPV TTVGPSRDGT ISEDTIRASL ISAVSDKLRW
RMKEEMDRAQ AELNALKRTE EDLKKGHQKL EEMVTRLDQE VAEVDKNIEL LKKKDEELSS
ALEKMENQSE NNDIDEVIIP TAPLYKQILN LYAEENAIED TIFYLGEALR RGVIDLDVFL
KHVRLLSRKQ FQLRALMQKA RKTAGLSDLY

The same domains may appear in multiple rows, following InterPro convention.

Start	End	Type	Name	InterPro	Source
1	145	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	G3DSA:3.10.110.10
2	145	Domain	Ubiquitin E2 variant, N-terminal	IPR008883	PS51322
3	141	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	SSF54495
22	141	Domain	Ubiquitin E2 variant, N-terminal	IPR008883	PF05743
316	379	Domain	Steadiness box (SB) domain	IPR017916	PF09454
322	390	Domain	Steadiness box (SB) domain	IPR017916	PS51312
323	383	Homologous_superfamily	ESCRT assembly domain	IPR037202	SSF140111

GO term	Name	Ontology	Evidence	Reference
GO:0015031	protein transport	Biological Process	IEA	GO_REF:0000120
GO:0016236	macroautophagy	Biological Process	IEA	GO_REF:0000117
GO:0036258	multivesicular body assembly	Biological Process	IEA	GO_REF:0000117
GO:0039702	viral budding via host ESCRT complex	Biological Process	IEA	GO_REF:0000117
GO:0000122	negative regulation of transcription by RNA polymerase II	Biological Process	IEA	GO_REF:0000107
GO:0001558	regulation of cell growth	Biological Process	IEA	GO_REF:0000107
GO:0008285	negative regulation of cell population proliferation	Biological Process	IEA	GO_REF:0000107
GO:0030154	cell differentiation	Biological Process	IEA	GO_REF:0000107
GO:0030216	keratinocyte differentiation	Biological Process	IEA	GO_REF:0000107
GO:0051726	regulation of cell cycle	Biological Process	IEA	GO_REF:0000107
GO:0006858	extracellular transport	Biological Process	IMP	PMID:22315426
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	Biological Process	IMP	PMID:16973552
GO:0008333	endosome to lysosome transport	Biological Process	IBA	GO_REF:0000033
GO:0019076	viral release from host cell	Biological Process	IMP	PMID:11595185
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	Biological Process	IMP	PMID:16554368
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	Biological Process	IDA	PMID:15611048
GO:0043328	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	Biological Process	NAS	PMID:32424346
GO:0043405	regulation of MAP kinase activity	Biological Process	IMP	PMID:17714434
GO:0046755	viral budding	Biological Process	ISS	GO_REF:0000024
GO:0051301	cell division	Biological Process	IEA	GO_REF:0000043
GO:0090148	membrane fission	Biological Process	NAS	PMID:32424346
GO:0097352	autophagosome maturation	Biological Process	TAS	PMID:21118109
GO:1903543	positive regulation of exosomal secretion	Biological Process	IMP	PMID:22660413
GO:1903551	regulation of extracellular exosome assembly	Biological Process	IMP	PMID:24105262
GO:1903774	positive regulation of viral budding via host ESCRT complex	Biological Process	IMP	PMID:11595185
GO:1990182	exosomal secretion	Biological Process	IEA	GO_REF:0000107
GO:2000397	positive regulation of ubiquitin-dependent endocytosis	Biological Process	IEA	GO_REF:0000107
GO:0005730	nucleolus	Cellular Component	IDA	GO_REF:0000052
GO:0005768	endosome	Cellular Component	IEA	GO_REF:0000043
GO:0005829	cytosol	Cellular Component	IDA	GO_REF:0000052
GO:0005886	plasma membrane	Cellular Component	IDA	GO_REF:0000052
GO:0031902	late endosome membrane	Cellular Component	IEA	GO_REF:0000044
GO:0000813	ESCRT I complex	Cellular Component	IEA	GO_REF:0000117
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000117
GO:0031982	vesicle	Cellular Component	IEA	GO_REF:0000117
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0005769	early endosome	Cellular Component	IDA	PMID:11916981
GO:0005770	late endosome	Cellular Component	IMP	PMID:15126635
GO:0005771	multivesicular body	Cellular Component	TAS	PMID:15611048
GO:0005813	centrosome	Cellular Component	IEA	GO_REF:0000044
GO:0005856	cytoskeleton	Cellular Component	IEA	GO_REF:0000043
GO:0010008	endosome membrane	Cellular Component	NAS	PMID:32424346
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0031901	early endosome membrane	Cellular Component	IEA	GO_REF:0000044
GO:0070062	extracellular exosome	Cellular Component	IEA	GO_REF:0000107
GO:0090543	Flemming body	Cellular Component	IEA	GO_REF:0000044
GO:0003677	DNA binding	Molecular Function	TAS	PMID:10888872
GO:0003714	transcription corepressor activity	Molecular Function	IEA	GO_REF:0000107
GO:0005515	protein binding	Molecular Function	IPI	PMID:12802020
GO:0031625	ubiquitin protein ligase binding	Molecular Function	IPI	PMID:17229889
GO:0042803	protein homodimerization activity	Molecular Function	IPI	PMID:14519844
GO:0043130	ubiquitin binding	Molecular Function	IBA	GO_REF:0000033
GO:0044877	protein-containing complex binding	Molecular Function	IDA	PMID:16973552
GO:0046790	virion binding	Molecular Function	IDA	PMID:11595185
GO:0048306	calcium-dependent protein binding	Molecular Function	IPI	PMID:19520058