RB40C

Details:

UniProt Entry: Q96S21
Gene: RAB40C
Class: Other E3 Components
Family: Receptor
Protein length: 281
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q96S21
MGSQGSPVKS YDYLLKFLLV GDSDVGKGEI LESLQDGAAE SPYAYSNGID YKTTTILLDG
RRVKLELWDT SGQGRFCTIF RSYSRGAQGI LLVYDITNRW SFDGIDRWIK EIDEHAPGVP
RILVGNRLHL AFKRQVPTEQ ARAYAEKNCM TFFEVSPLCN FNVIESFTEL SRIVLMRHGM
EKIWRPNRVF SLQDLCCRAI VSCTPVHLID KLPLPVTIKS HLKSFSMANG MNAVMMHGRS
YSLASGAGGG GSKGNSLKRS KSIRPPQSPP QNCSRSNCKI S

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	236	Family	Small GTPase	IPR001806	PS51421
6	189	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	IPR027417	G3DSA:3.40.50.300
10	189	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	IPR027417	SSF52540
15	157	Domain	Small GTP-binding protein domain	IPR005225	TIGR00231
16	174	Family	Small GTPase	IPR001806	PF00071
17	177	Family	Small GTPase	IPR001806	SM00174
175	228	Domain	SOCS box domain	IPR001496	PS50225
183	226	Domain	SOCS box domain	IPR001496	SM00253
189	225	Domain	SOCS box domain	IPR001496	SM00969
189	223	Domain	SOCS box domain	IPR001496	PF07525
189	228	Homologous_superfamily	SOCS box-like domain superfamily	IPR036036	SSF158235

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0035556	intracellular signal transduction	Biological Process	IEA	GO_REF:0000002
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:35512830
GO:0051894	positive regulation of focal adhesion assembly	Biological Process	IMP	PMID:35512830
GO:0051895	negative regulation of focal adhesion assembly	Biological Process	IDA	PMID:35512830
GO:0006887	exocytosis	Biological Process	IBA	GO_REF:0000033
GO:0016477	cell migration	Biological Process	IMP	PMID:35512830
GO:0140042	lipid droplet formation	Biological Process	IMP	PMID:29156729
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000117
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000120
GO:0005794	Golgi apparatus	Cellular Component	IDA	PMID:34469730
GO:0005811	lipid droplet	Cellular Component	IDA	PMID:34469730
GO:0005768	endosome	Cellular Component	IBA	GO_REF:0000033
GO:0005886	plasma membrane	Cellular Component	IBA	GO_REF:0000033
GO:0008021	synaptic vesicle	Cellular Component	IBA	GO_REF:0000033
GO:0000139	Golgi membrane	Cellular Component	IEA	GO_REF:0000044
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000044
GO:0031466	Cul5-RING ubiquitin ligase complex	Cellular Component	IMP	PMID:35512830
GO:0000166	nucleotide binding	Molecular Function	IEA	GO_REF:0000043
GO:0003924	GTPase activity	Molecular Function	IEA	GO_REF:0000002
GO:0005525	GTP binding	Molecular Function	IEA	GO_REF:0000120
GO:0003925	G protein activity	Molecular Function	IMP	PMID:29156729
GO:0005515	protein binding	Molecular Function	IPI	PMID:35512830
GO:0016787	hydrolase activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IMP	PMID:35512830

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