ASB16

Details:

UniProt Entry: Q96NS5
Gene: ASB16
Class: Other E3 Components
Family: Receptor
Protein length: 453
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q96NS5
MARETFPFTS SMLRSLRLQQ EWLEWEDRRR AAAQQCRSRR CPSSPRARLT RPHRSCRDPA
VHQALFSGNL QQVQALFQDE EAANMIVETV SNQLAWSAEQ GFWVLTPKTK QTAPLAIATA
RGYTDCARHL IRQGAELDAR VGGRAALHEA CARAQFDCVR LLLTFGAKAN VLTEEGTTPL
HLCTIPESLQ CAKLLLEAGA TVNLAAGESQ ETPLHVAAAR GLEQHVALYL EHGADVGLRT
SQGETALNTA CAGAEGPGSC RRHQAAARRL LEAGADARAA GRKRHTPLHN ACANGCGGLA
ELLLRYGARA EVPNGAGHTP MDCALQAVQD SPNWEPEVLF AALLDYGAQP VRPEMLKHCA
NFPRALEVLL NAYPCVPSCE TWVEAVLPEL WKEHEAFYSS ALCMVNQPRQ LQHLARLAVR
ARLGSRCRQG ATRLPLPPLL RDYLLLRVEG CIQ

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
53	179	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
61	326	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	SSF48403
110	139	Repeat	Ankyrin repeat	IPR002110	SM00248
115	204	Repeat	Ankyrin repeat	IPR002110	PF12796
142	174	Repeat	Ankyrin repeat	IPR002110	PS50088
142	171	Repeat	Ankyrin repeat	IPR002110	SM00248
175	204	Repeat	Ankyrin repeat	IPR002110	SM00248
175	207	Repeat	Ankyrin repeat	IPR002110	PS50088
180	259	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
209	241	Repeat	Ankyrin repeat	IPR002110	PS50088
209	238	Repeat	Ankyrin repeat	IPR002110	SM00248
229	311	Repeat	Ankyrin repeat	IPR002110	PF12796
242	279	Repeat	Ankyrin repeat	IPR002110	SM00248
260	333	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
283	315	Repeat	Ankyrin repeat	IPR002110	PS50088
283	312	Repeat	Ankyrin repeat	IPR002110	SM00248
316	352	Repeat	Ankyrin repeat	IPR002110	SM00248
404	446	Homologous_superfamily	SOCS box-like domain superfamily	IPR036036	SSF158235
406	444	Domain	SOCS box domain	IPR001496	PS50225
407	445	Domain	SOCS box domain	IPR001496	PF07525
408	447	Domain	SOCS box domain	IPR001496	SM00969

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0035556	intracellular signal transduction	Biological Process	IEA	GO_REF:0000002
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000117
GO:0005515	protein binding	Molecular Function	IPI	PMID:17474147

Data Usage Statement and License Agreement

Ownership and Copyright

The Database, including all associated datasets, metadata, and documentation, is the intellectual property of the PROXIDRUGs consortium and the InnoDATA project.
The content of the Database is protected under applicable copyright and database protection laws.

Permitted Use

The Database is provided for research, academic, and non-commercial purposes only, unless explicitly stated otherwise.
Users are permitted to:
- Access, download, and use the data.
- Modify or build upon the data for academic, educational, or scientific purposes.
- Share derived datasets, analyses, or visualizations with proper citation and explicit acknowledgment of “The Human E3 Ligome” project.

Prohibited Use

Use the Database or any derivative works for commercial purposes without prior written consent from the PROXIDRUGs consortia (InnoDATA PIs).
Redistribute or republish the Database (or substantial parts of it) without proper credit and adherence to the license terms.
Misrepresent the data, alter metadata to mislead, or use it in a way that violates ethical or scientific standards.

Licensing

Unless otherwise stated, the Database is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0).
This license allows redistribution and adaptation, provided appropriate credit is given.
Contributions (e.g., data corrections, additions, or scripts) can be made through merge requests on GitLab.
Contributors must agree to license their contributions under the same CC BY 4.0 license.

Citation Requirements

If you use or refer to the Database in your publications, reports, or presentations, you must cite the paper: Dutta et al. (2025, preprint)

Contact and Support

For inquiries, permissions, or support regarding the Database, please contact: Dr. Ramachandra M. Bhaskara, Goethe University Frankfurt.
Email: bhaskara@med.uni-frankfurt.de.
Website maintained by Alberto Cristiani, Arghya Dutta, and Siddhanta V. Nikte.