KCTD7

Details:

UniProt Entry: Q96MP8
Gene: KCTD7
Class: Other E3 Components
Family: Adaptor
Protein length: 289
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q96MP8
MVVVTGREPD SRRQDGAMSS SDAEDDFLEP ATPTATQAGH ALPLLPQEFP EVVPLNIGGA
HFTTRLSTLR CYEDTMLAAM FSGRHYIPTD SEGRYFIDRD GTHFGDVLNF LRSGDLPPRE
RVRAVYKEAQ YYAIGPLLEQ LENMQPLKGE KVRQAFLGLM PYYKDHLERI VEIARLRAVQ
RKARFAKLKV CVFKEEMPIT PYECPLLNSL RFERSESDGQ LFEHHCEVDV SFGPWEAVAD
VYDLLHCLVT DLSAQGLTVD HQCIGVCDKH LVNHYYCKRP IYEFKITWW

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
47	147	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
51	149	Domain	BTB/POZ domain	IPR000210	SM00225
51	144	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
53	138	Domain	Potassium channel tetramerisation-type BTB domain	IPR003131	PF02214

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0051260	protein homooligomerization	Biological Process	IEA	GO_REF:0000002
GO:0030007	intracellular potassium ion homeostasis	Biological Process	IEA	GO_REF:0000107
GO:0060081	membrane hyperpolarization	Biological Process	IBA	GO_REF:0000033
GO:0090461	intracellular glutamate homeostasis	Biological Process	IMP	PMID:27742667
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000044
GO:0005886	plasma membrane	Cellular Component	IEA	GO_REF:0000044
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000043
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0042802	identical protein binding	Molecular Function	IEA	GO_REF:0000117
GO:0005515	protein binding	Molecular Function	IPI	PMID:22748208

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