FXL18

Details:

UniProt Entry: Q96ME1
Gene: FBXL18
Class: Other E3 Components
Family: Receptor
Protein length: 805
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q96ME1
MASSGEDISN DDDDMHPAAA GMADGVHLLG FSDEILLHIL SHVPSTDLIL NVRRTCRKLA
ALCLDKSLIH TVLLQKDYQA SEDKVRQLVK EIGREIQQLS MAGCYWLPGS TVEHVARCRS
LVKVNLSGCH LTSLRLSKML SALQHLRSLA IDVSPGFDAS QLSSECKATL SRVRELKQTL
FTPSYGVVPC CTSLEKLLLY FEILDRTREG AILSGQLMVG QSNVPHYQNL RVFYARLAPG
YINQEVVRLY LAVLSDRTPQ NLHAFLISVP GSFAESGATK NLLDSMARNV VLDALQLPKS
WLNGSSLLQH MKFNNPFYFS FSRCTLSGGH LIQQVINGGK DLRSLASLNL SGCVHCLSPD
SLLRKAEDDI DSSILETLVA SCCNLRHLNL SAAHHHSSEG LGRHLCQLLA RLRHLRSLSL
PVCSVADSAP RADRAPAQPA MHAVPRGFGK KVRVGVQSCP SPFSGQACPQ PSSVFWSLLK
NLPFLEHLEL IGSNFSSAMP RNEPAIRNSL PPCSRAQSVG DSEVAAIGQL AFLRHLTLAQ
LPSVLTGSGL VNIGLQCQQL RSLSLANLGM MGKVVYMPAL SDMLKHCKRL RDLRLEQPYF
SANAQFFQAL SQCPSLQRLC LVSRSGTLQP DAVLAFMARC LQVVMCHLFT GESLATCKSL
QQSLLRRWGE VTGRRPQLFT ELREEPSART SRATGRRQPC LPDSGVVCCP CGRPLAVSGI
ILVGVSPSLV VKTTCVYRVL FKNLDYASIF FLVCLFETES HSVVQAGVQW RDLSSLQPLL
SGLQPQPPEQ LENELEIGFS YCFVI

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
13	75	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
23	201	Homologous_superfamily	Leucine-rich repeat domain superfamily	IPR032675	G3DSA:3.80.10.10
25	72	Domain	F-box domain	IPR001810	PS50181
30	68	Domain	F-box domain	IPR001810	PF00646
85	669	Domain	F-box/LRR-repeat protein 18, LRR domain	IPR045627	PF19729
261	432	Homologous_superfamily	Leucine-rich repeat domain superfamily	IPR032675	G3DSA:3.80.10.10
468	680	Homologous_superfamily	Leucine-rich repeat domain superfamily	IPR032675	G3DSA:3.80.10.10

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IEA	GO_REF:0000002
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8854051
GO:0005515	protein binding	Molecular Function	IPI	PMID:16189514

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