KCNS1

Details:

UniProt Entry: Q96KK3
Gene: KCNS1
Class: Other E3 Components
Family: Adaptor
Protein length: 526
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q96KK3
MLMLLVRGTH YENLRSKVVL PTPLGGRSTE TFVSEFPGPD TGIRWRRSDE ALRVNVGGVR
RQLSARALAR FPGTRLGRLQ AAASEEQARR LCDDYDEAAR EFYFDRHPGF FLSLLHFYRT
GHLHVLDELC VFAFGQEADY WGLGENALAA CCRARYLERR LTQPHAWDED SDTPSSVDPC
PDEISDVQRE LARYGAARCG RLRRRLWLTM ENPGYSLPSK LFSCVSISVV LASIAAMCIH
SLPEYQAREA AAAVAAVAAG RSPEGVRDDP VLRRLEYFCI AWFSFEVSSR LLLAPSTRNF
FCHPLNLIDI VSVLPFYLTL LAGVALGDQG GKEFGHLGKV VQVFRLMRIF RVLKLARHST
GLRSLGATLK HSYREVGILL LYLAVGVSVF SGVAYTAEKE EDVGFNTIPA CWWWGTVSMT
TVGYGDVVPV TVAGKLAASG CILGGILVVA LPITIIFNKF SHFYRRQKAL EAAVRNSNHQ
EFEDLLSSID GVSEASLETS RETSQEGQSA DLESQAPSEP PHPQMY

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
39	162	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
50	159	Domain	BTB/POZ domain	IPR000210	SM00225
50	159	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
52	151	Domain	Potassium channel tetramerisation-type BTB domain	IPR003131	PF02214
55	67	Family	Potassium channel, voltage dependent, Kv9	IPR003971	PR01494
70	86	Family	Potassium channel, voltage dependent, Kv9	IPR003971	PR01494
93	106	Family	Potassium channel, voltage dependent, Kv9	IPR003971	PR01494
101	111	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491
117	132	Family	Potassium channel, voltage dependent, Kv9	IPR003971	PR01494
140	152	Family	Potassium channel, voltage dependent, Kv9	IPR003971	PR01494
195	358	Homologous_superfamily	Voltage-dependent channel domain superfamily	IPR027359	G3DSA:1.20.120.350
220	467	Domain	Ion transport domain	IPR005821	PF00520
226	238	Family	Potassium channel, voltage dependent, Kv9	IPR003971	PR01494
351	359	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491
375	389	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491
444	462	Family	Potassium channel, voltage dependent, Kv9	IPR003971	PR01494
445	456	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006811	monoatomic ion transport	Biological Process	IEA	GO_REF:0000120
GO:0006813	potassium ion transport	Biological Process	IEA	GO_REF:0000120
GO:0034220	monoatomic ion transmembrane transport	Biological Process	IEA	GO_REF:0000043
GO:0051260	protein homooligomerization	Biological Process	IEA	GO_REF:0000002
GO:0055085	transmembrane transport	Biological Process	IEA	GO_REF:0000002
GO:0071805	potassium ion transmembrane transport	Biological Process	IEA	GO_REF:0000043
GO:1901379	regulation of potassium ion transmembrane transport	Biological Process	IEA	GO_REF:0000120
GO:0001508	action potential	Biological Process	IBA	GO_REF:0000033
GO:0005654	nucleoplasm	Cellular Component	IDA	GO_REF:0000052
GO:0005886	plasma membrane	Cellular Component	IDA	GO_REF:0000052
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000120
GO:0048471	perinuclear region of cytoplasm	Cellular Component	IEA	GO_REF:0000107
GO:0008076	voltage-gated potassium channel complex	Cellular Component	IEA	GO_REF:0000120
GO:0034702	monoatomic ion channel complex	Cellular Component	IEA	GO_REF:0000043
GO:0005216	monoatomic ion channel activity	Molecular Function	IEA	GO_REF:0000002
GO:0005249	voltage-gated potassium channel activity	Molecular Function	IEA	GO_REF:0000002
GO:0005267	potassium channel activity	Molecular Function	IEA	GO_REF:0000043
GO:0015459	potassium channel regulator activity	Molecular Function	IEA	GO_REF:0000120
GO:0005515	protein binding	Molecular Function	IPI	PMID:10484328

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