ZBT45

Details:

UniProt Entry: Q96K62
Gene: ZBTB45
Class: RING
Family: RING6
Protein length: 511
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>Q96K62
MAAAEAVHHI HLQNFSRSLL ETLNGQRLGG HFCDVTVRIR EASLRAHRCV LAAGSPFFQD
KLLLGHSEIR VPPVVPAQTV RQLVEFLYSG SLVVAQGEAL QVLTAASVLR IQTVIDECTQ
IIARARAPGT SAPTPLPTPV PPPLAPAQLR HRLRHLLAAR PPGHPGAAHS RKQRQPARLQ
LPAPPTPAKA EGPDADPSLS AAPDDRGDED DEESDDETDG EDGEGGGPGE GQAPPSFPDC
AAGFLTAAAD SACEEPPAPT GLADYSGAGR DFLRGAGSAE DVFPDSYVST WHDEDGAVPE
GCPTETPVQP DCILSGSRPP GVKTPGPPVA LFPFHLGAPG PPAPPPSAPS GPAPAPPPAF
YPTLQPEAAP STQLGEVPAP SAAPTTAPSG TPARTPGAEP PTYECSHCRK TFSSRKNYTK
HMFIHSGEKP HQCAVCWRSF SLRDYLLKHM VTHTGVRAFQ CAVCAKRFTQ KSSLNVHMRT
HRPERAPCPA CGKVFSHRAL LERHLAAHPA P

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
7	132	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
8	123	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
23	122	Domain	BTB/POZ domain	IPR000210	PF00651
33	126	Domain	BTB/POZ domain	IPR000210	SM00225
33	96	Domain	BTB/POZ domain	IPR000210	PS50097
402	453	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
403	425	Domain	Zinc finger C2H2-type	IPR013087	PF00096
403	430	Domain	Zinc finger C2H2-type	IPR013087	PS50157
403	425	Domain	Zinc finger C2H2-type	IPR013087	SM00355
405	425	Domain	Zinc finger C2H2-type	IPR013087	PS00028
431	453	Domain	Zinc finger C2H2-type	IPR013087	SM00355
431	453	Domain	Zinc finger C2H2-type	IPR013087	PF00096
431	458	Domain	Zinc finger C2H2-type	IPR013087	PS50157
433	453	Domain	Zinc finger C2H2-type	IPR013087	PS00028
439	495	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
459	481	Domain	Zinc finger C2H2-type	IPR013087	PF00096
459	481	Domain	Zinc finger C2H2-type	IPR013087	SM00355
459	486	Domain	Zinc finger C2H2-type	IPR013087	PS50157
461	481	Domain	Zinc finger C2H2-type	IPR013087	PS00028
486	511	Domain	Zinc finger C2H2-type	IPR013087	PS50157
486	508	Domain	Zinc finger C2H2-type	IPR013087	SM00355
487	508	Domain	Zinc finger C2H2-type	IPR013087	PF00096
488	508	Domain	Zinc finger C2H2-type	IPR013087	PS00028

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0000122	negative regulation of transcription by RNA polymerase II	Biological Process	IBA	GO_REF:0000033
GO:0001817	regulation of cytokine production	Biological Process	IBA	GO_REF:0000033
GO:0002682	regulation of immune system process	Biological Process	IBA	GO_REF:0000033
GO:0007399	nervous system development	Biological Process	IEA	GO_REF:0000043
GO:0005654	nucleoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Molecular Function	IBA	GO_REF:0000033
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Molecular Function	IBA	GO_REF:0000033
GO:0003677	DNA binding	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:32296183
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:1990837	sequence-specific double-stranded DNA binding	Molecular Function	IEA	GO_REF:0000117

Enzyme–Substrate Interactions ▾

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