RN170

>Q96K19
MAKYQGEVQS LKLDDDSVIE GVSDQVLVAV VVSFALIATL VYALFRNVHQ NIHPENQELV
RVLREQLQTE QDAPAATRQQ FYTDMYCPIC LHQASFPVET NCGHLFCGAC IIAYWRYGSW
LGAISCPICR QTVTLLLTVF GEDDQSQDVL RLHQDINDYN RRFSGQPRSI MERIMDLPTL
LRHAFREMFS VGGLFWMFRI RIILCLMGAF FYLISPLDFV PEALFGILGF LDDFFVIFLL
LIYISIMYRE VITQRLTR

The same domains may appear in multiple rows, following InterPro convention.

Start	End	Type	Name	InterPro	Source
1	257	Family	E3 ubiquitin-protein ligase RNF170	IPR038896	PTHR22894
43	156	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
87	129	Domain	Zinc finger, RING-type	IPR001841	SM00184
87	129	Domain	Zinc finger, C3HC4 RING-type	IPR018957	PF00097
87	130	Domain	Zinc finger, RING-type	IPR001841	PS50089
102	111	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
203	239	Domain	Domain of unknown function DUF1232	IPR010652	PF06803

GO term	Name	Ontology	Evidence	Reference
GO:0000209	protein polyubiquitination	Biological Process	IEA	GO_REF:0000107
GO:0007628	adult walking behavior	Biological Process	IEA	GO_REF:0000107
GO:0009266	response to temperature stimulus	Biological Process	IEA	GO_REF:0000107
GO:0010467	gene expression	Biological Process	IEA	GO_REF:0000107
GO:0010498	proteasomal protein catabolic process	Biological Process	IEA	GO_REF:0000107
GO:0014823	response to activity	Biological Process	IEA	GO_REF:0000107
GO:0030163	protein catabolic process	Biological Process	IEA	GO_REF:0000107
GO:0034138	toll-like receptor 3 signaling pathway	Biological Process	IEA	GO_REF:0000107
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IEA	GO_REF:0000107
GO:0045087	innate immune response	Biological Process	IEA	GO_REF:0000107
GO:0070936	protein K48-linked ubiquitination	Biological Process	IEA	GO_REF:0000107
GO:0090659	walking behavior	Biological Process	IEA	GO_REF:0000107
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0005783	endoplasmic reticulum	Cellular Component	IEA	GO_REF:0000043
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IEA	GO_REF:0000044
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000002
GO:0005515	protein binding	Molecular Function	IPI	PMID:25416956

Substrate	Name	Known ESI (UbiBrowser)	Known ESI (UbiNet)	PPI (IntAct direct) PSI-MI score ≥ 0.5	PPI (IntAct indirect) PSI-MI scores ≥ 0.5 for both PPIs	PubMed Ref.	IntAct Ref.	Substrate Specificity
Q14643	ITPR1	Yes	Yes	No	No	—	No	E3-specific