RNFT2

Details:

UniProt Entry: Q96EX2
Gene: RNFT2
Class: RING
Family: RING4
Protein length: 444
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>Q96EX2
MWLFTVNQVL RKMQRRHSSN TDNIPPERNR SQALSSEASV DEGGVFESLK AEAASPPALF
SGLSGSLPTS SFPSSLVLGS SAGGGDVFIQ MPASREEGGG RGEGGAYHHR QPHHHFHHGG
HRGGSLLQHV GGDHRGHSEE GGDEQPGTPA PALSELKAVI CWLQKGLPFI LILLAKLCFQ
HKLGIAVCIG MASTFAYANS TLREQVSLKE KRSVLVILWI LAFLAGNTLY VLYTFSSQQL
YNSLIFLKPN LEMLDFFDLL WIVGIADFVL KYITIALKCL IVALPKIILA VKSKGKFYLV
IEELSQLFRS LVPIQLWYKY IMGDDSSNSY FLGGVLIVLY SLCKSFDICG RVGGVRKALK
LLCTSQNYGV RATGQQCTEA GDICAICQAE FREPLILLCQ HVFCEECLCL WLDRERTCPL
CRSVAVDTLR CWKDGATSAH FQVY

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
31	444	Family	RING finger and transmembrane domain-containing protein 1/2	IPR044235	PTHR15860
361	430	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
384	422	Domain	Zinc finger, RING-type	IPR001841	PS50089
384	421	Domain	Zinc finger, RING-type	IPR001841	SM00184
399	408	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:1904294	positive regulation of ERAD pathway	Biological Process	IEA	GO_REF:0000002
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000002

Enzyme–Substrate Interactions ▾


P26951	IL3RA	Yes	No	No	No	—	No	E3-specific

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