FBX17

Details:

UniProt Entry: Q96EF6
Gene: FBXO17
Class: Other E3 Components
Family: Receptor
Protein length: 278
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q96EF6
MGARLSRRRL PADPSLALDA LPPELLVQVL SHVPPRSLVT RCRPVCRAWR DIVDGPTVWL
LQLARDRSAE GRALYAVAQR CLPSNEDKEE FPLCALARYC LRAPFGRNLI FNSCGEQGFR
GWEVEHGGNG WAIEKNLTPV PGAPSQTCFV TSFEWCSKRQ LVDLVMEGVW QELLDSAQIE
ICVADWWGAR ENCGCVYQLR VRLLDVYEKE VVKFSASPDP VLQWTERGCR QVSHVFTNFG
KGIRYVSFEQ YGRDVSSWVG HYGALVTHSS VRVRIRLS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
4	276	Family	F-box only protein	IPR039752	PTHR12125
8	69	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
15	62	Domain	F-box domain	IPR001810	PS50181
19	59	Domain	F-box domain	IPR001810	PF12937
21	62	Domain	F-box domain	IPR001810	SM00256
93	275	Domain	F-box associated (FBA) domain	IPR007397	SM01198
97	274	Homologous_superfamily	Galactose-binding-like domain superfamily	IPR008979	SSF49785
99	275	Domain	F-box associated (FBA) domain	IPR007397	PS51114
100	273	Domain	F-box associated (FBA) domain	IPR007397	PF04300

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006516	glycoprotein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0036503	ERAD pathway	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000117
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8952618
GO:0019005	SCF ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IDA	PMID:18203720

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