KLH29

Details:

UniProt Entry: Q96CT2
Gene: KLHL29
Class: Other E3 Components
Family: Adaptor
Protein length: 875
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q96CT2
MSRHHSRFER DYRVGWDRRE WSVNGTHGTT SICSVTSGAG GGTASSLSVR PGLLPLPVVP
SRLPTPATAP APCTTGSSEA ITSLVASSAS AVTTKAPGIS KGDSQSQGLA TSIRWGQTPI
NQSTPWDTDE PPSKQMRESD NPGTGPWVTT VAAGNQPTLI AHSYGVAQPP TFSPAVNVQA
PVIGVTPSLP PHVGPQLPLM PGHYSLPQPP SQPLSSVVVN MPAQALYASP QPLAVSTLPG
VGQVARPGPT AVGNGHMAGP LLPPPPPAQP SATLPSGAPA TNGPPTTDSA HGLQMLRTIG
VGKYEFTDPG HPREMLKELN QQRRAKAFTD LKIVVEGREF EVHQNVLASC SLYFKDLIQR
SVQDSGQGGR EKLELVLSNL QADVLELLLE FVYTGSLVID SANAKTLLEA ASKFQFHTFC
KVCVSFLEKQ LTASNCLGVL AMAEAMQCSE LYHMAKAFAL QIFPEVAAQE EILSISKDDF
IAYVSNDSLN TKAEELVYET VIKWIKKDPA TRTQYAAELL AVVRLPFIHP SYLLNVVDNE
ELIKSSEACR DLVNEAKRYH MLPHARQEMQ TPRTRPRLSA GVAEVIVLVG GRQMVGMTQR
SLVAVTCWNP QNNKWYPLAS LPFYDREFFS VVSAGDNIYL SGGMESGVTL ADVWCYMSLL
DNWNLVSRMT VPRCRHNSLV YDGKIYTLGG LGVAGNVDHV ERYDTITNQW EAVAPLPKAV
HSAAATVCGG KIYVFGGVNE AGRAAGVLQS YVPQTNTWSF IESPMIDNKY APAVTLNGFV
FILGGAYARA TTIYDPEKGN IKAGPNMNHS RQFCSAVVLD GKIYATGGIV SSEGPALGNM
EAYEPTTNTW TLLPHMPCPV FRHGCVVIKK YIQSG

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
301	432	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
306	429	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
319	430	Domain	BTB/POZ domain	IPR000210	PF00651
329	401	Domain	BTB/POZ domain	IPR000210	PS50097
329	431	Domain	BTB/POZ domain	IPR000210	SM00225
436	538	Domain	BTB/Kelch-associated	IPR011705	SM00875
436	537	Domain	BTB/Kelch-associated	IPR011705	PF07707
551	745	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
585	636	Repeat	Kelch repeat type 1	IPR006652	SM00612
596	868	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
637	683	Repeat	Kelch repeat type 1	IPR006652	SM00612
672	717	Repeat	Kelch repeat type 1	IPR006652	PF01344
684	730	Repeat	Kelch repeat type 1	IPR006652	SM00612
722	764	Repeat	Kelch repeat type 1	IPR006652	PF01344
731	778	Repeat	Kelch repeat type 1	IPR006652	SM00612
746	872	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
779	821	Repeat	Kelch repeat type 1	IPR006652	SM00612
811	857	Repeat	Kelch repeat type 1	IPR006652	PF01344
822	870	Repeat	Kelch repeat type 1	IPR006652	SM00612

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0031463	Cul3-RING ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:25036637
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IBA	GO_REF:0000033

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