ARMC5

Details:

UniProt Entry: Q96C12
Gene: ARMC5
Class: Other E3 Components
Family: Adaptor
Protein length: 935
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q96C12
MAAAKPTLTD SLSFCLAQLA AAAGEALGGE KDPATNETPL SRALLALRTR HIKAAGGIER
FRARGGLRPL LALLRRAAAA GSAPSQAGPG SAPSSAASGA SSPAPASGPA PSAVSSSSPT
PPVRLRKTLD LALSILADCC TEGACRTEVR RLGGILPLVT ILQCMKTDSI QNRTARALGN
LAMEPESCGD IHCAGAVPLL VESLTACQDS QCLQSVVRAL RNLADSPQHR LALAQQGAVR
PLAELLATAP DAALTLALVR ALLELSRGCS RACAEQLSLG GGLGPLVSLA SHPKRAVREG
TILILANLCA QGLIRPALGN AGGVEVLVDE LRQRRDPNGA SPTSQQPLVR AVCLLCREAI
NRARLRDAGG LDLLMGLLRD PRASAWHPRI VAALVGFLYD TGALGRLQAL GLVPLLAGQL
CGEAGEEEEE GREAASWDFP EERTPERAQG GSFRSLRSWL ISEGYATGPD DISPDWSPEQ
CPPEPMEPAS PAPTPTSLRA PRTQRTPGRS PAAAIEEPWG REGPALLLLS RFSQAPDPSG
ALVTGPALYG LLTYVTGAPG PPSPRALRIL SRLTCNPACL EAFVRSYGAA LLRAWLVLGV
APDDWPAPRA RPTLHSRHRE LGERLLQNLT VQAESPFGVG ALTHLLLSGS PEDRVACALT
LPFICRKPSL WRRLLLEQGG LRLLLAALTR PAPHPLFLFF AADSLSCLQD LVSPTVSPAV
PQAVPMDLDS PSPCLYEPLL GPAPVPAPDL HFLLDSGLQL PAQRAASATA SPFFRALLSG
SFAEAQMDLV PLRGLSPGAA WPVLHHLHGC RGCGAALGPV PPPGQPLLGS EAEEALEAAG
RFLLPGLEEE LEEAVGRIHL GPQGGPESVG EVFRLGRPRL AAHCARWTLG SEQCPRKRGL
ALVGLVEAAG EEAGPLTEAL LAVVMGIELG ARVPA

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
18	462	Homologous_superfamily	Armadillo-like helical	IPR011989	G3DSA:1.25.10.10
132	706	Homologous_superfamily	Armadillo-type fold	IPR016024	SSF48371
141	183	Repeat	Armadillo	IPR000225	SM00185
184	225	Repeat	Armadillo	IPR000225	SM00185
195	238	Repeat	Armadillo	IPR000225	PS50176
226	267	Repeat	Armadillo	IPR000225	SM00185
310	357	Repeat	Armadillo	IPR000225	SM00185
358	403	Repeat	Armadillo	IPR000225	SM00185
746	888	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
748	808	Domain	BTB/POZ domain	IPR000210	PS50097

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0001701	in utero embryonic development	Biological Process	IEA	GO_REF:0000107
GO:0001707	mesoderm formation	Biological Process	IEA	GO_REF:0000107
GO:0006366	transcription by RNA polymerase II	Biological Process	IDA	PMID:9852112
GO:0006368	transcription elongation by RNA polymerase II	Biological Process	IDA	PMID:9852112
GO:0007369	gastrulation	Biological Process	IEA	GO_REF:0000107
GO:0030097	hemopoiesis	Biological Process	IEA	GO_REF:0000107
GO:0035801	adrenal cortex development	Biological Process	IEA	GO_REF:0000107
GO:0042098	T cell proliferation	Biological Process	IEA	GO_REF:0000107
GO:0043367	CD4-positive, alpha-beta T cell differentiation	Biological Process	IEA	GO_REF:0000107
GO:0050810	regulation of steroid biosynthetic process	Biological Process	IEA	GO_REF:0000107
GO:0051607	defense response to virus	Biological Process	IEA	GO_REF:0000107
GO:0009653	anatomical structure morphogenesis	Biological Process	IBA	GO_REF:0000033
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IEA	GO_REF:0000107
GO:0160240	RNA polymerase II transcription initiation surveillance	Biological Process	IDA	PMID:39504960
GO:0005654	nucleoplasm	Cellular Component	IDA	GO_REF:0000052
GO:0005829	cytosol	Cellular Component	IDA	GO_REF:0000052
GO:0005925	focal adhesion	Cellular Component	IDA	GO_REF:0000052
GO:0000785	chromatin	Cellular Component	IDA	PMID:39667934
GO:0005634	nucleus	Cellular Component	IDA	PMID:35687106
GO:0005737	cytoplasm	Cellular Component	IDA	PMID:35862218
GO:0005694	chromosome	Cellular Component	IEA	GO_REF:0000120
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000107
GO:0031463	Cul3-RING ubiquitin ligase complex	Cellular Component	IDA	PMID:35687106
GO:0005515	protein binding	Molecular Function	IPI	PMID:28169274
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IEA	GO_REF:0000107

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