ZBT8A

Details:

UniProt Entry: Q96BR9
Gene: ZBTB8A
Class: RING
Family: RING6
Protein length: 441
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>Q96BR9
MEISSHQSHL LQQLNEQRRQ DVFCDCSILV EGKVFKAHRN VLFASSGYFK MLLSQNSKET
SQPTTATFQA FSPDTFTVIL DFVYSGKLSL TGQNVIEVMS AASFLQMTDV ISVCKTFIKS
SLDISEKEKD RYFSLSDKDA NSNGVERSSF YSGGWQEGSS SPRSHLSPEQ GTGIISGKSW
NKYNYHPASQ KNTQQPLAKH EPRKESIKKT KHLRLSQPSE VTHYKSSKRE VRTSDSSSHV
SQSEEQAQID AEMDSTPVGY QYGQGSDVTS KSFPDDLPRM RFKCPYCTHV VKRKADLKRH
LRCHTGERPY PCQACGKRFS RLDHLSSHFR TIHQACKLIC RKCKRHVTDL TGQVVQEGTR
RYRLCNECLA EFGIDSLPID LEAEQHLMSP SDGDKDSRWH LSEDENRSYV EIVEDGSADL
VIQQVDDSEE EEEKEIKPNI R

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	146	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
2	120	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
14	121	Domain	BTB/POZ domain	IPR000210	PF00651
24	122	Domain	BTB/POZ domain	IPR000210	SM00225
24	92	Domain	BTB/POZ domain	IPR000210	PS50097
282	304	Domain	Zinc finger C2H2-type	IPR013087	SM00355
282	309	Domain	Zinc finger C2H2-type	IPR013087	PS50157
282	302	Domain	Zinc finger C2H2-type	IPR013087	PF00096
282	331	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
284	304	Domain	Zinc finger C2H2-type	IPR013087	PS00028
310	333	Domain	Zinc finger C2H2-type	IPR013087	SM00355
310	333	Domain	Zinc finger C2H2-type	IPR013087	PF00096
310	338	Domain	Zinc finger C2H2-type	IPR013087	PS50157
312	333	Domain	Zinc finger C2H2-type	IPR013087	PS00028

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0000122	negative regulation of transcription by RNA polymerase II	Biological Process	IDA	PMID:23329847
GO:0006357	regulation of transcription by RNA polymerase II	Biological Process	IBA	GO_REF:0000033
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000044
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0000976	transcription cis-regulatory region binding	Molecular Function	IDA	PMID:23329847
GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Molecular Function	IBA	GO_REF:0000033
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Molecular Function	IBA	GO_REF:0000033
GO:0001223	transcription coactivator binding	Molecular Function	IPI	PMID:23329847
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Molecular Function	IDA	PMID:23329847
GO:0003677	DNA binding	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:16189514
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Molecular Function	IPI	PMID:23329847

Enzyme–Substrate Interactions ▾

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