TRI43

Details:

UniProt Entry: Q96BQ3
Gene: TRIM43
Class: RING
Family: RING5
Protein length: 446
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q96BQ3
MDSDFSHAFQ KELTCVICLN YLVDPVTICC GHSFCRPCLC LSWEEAQSPA NCPACREPSP
KMDFKTNILL KNLVTIARKA SLWQFLSSEK QICGTHRQTK KMFCDMDKSL LCLLCSNSQE
HGAHKHHPIE EAAEEHREKL LKQMRILWKK IQENQRNLYE EGRTAFLWRG NVVLRAQMIR
NEYRKLHPVL HKEEKQHLER LNKEYQEIFQ QLQRSWVKMD QKSKHLKEMY QELMEMCHKP
DVELLQDLGD IVARSESVLL HMPQPVNPEL TAGPITGLVY RLNRFRVEIS FHFEVTNHNI
RLFEDVRSWM FRRGPLNSDR SDYFAAWGAR VFSFGKHYWE LDVDNSCDWA LGVCNNSWIR
KNSTMVNSED IFLLLCLKVD NHFNLLTTSP VFPHYIEKPL GRVGVFLDFE SGSVSFLNVT
KSSLIWSYPA GSLTFPVRPF FYTGHR

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
4	82	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
15	55	Domain	Zinc finger, RING-type	IPR001841	SM00184
15	56	Domain	Zinc finger, RING-type	IPR001841	PS50089
30	39	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
88	129	Domain	B-box-type zinc finger	IPR000315	PS50119
88	129	Domain	B-box-type zinc finger	IPR000315	SM00336
269	446	Domain	B30.2/SPRY domain	IPR001870	PS50188
280	446	Homologous_superfamily	B30.2/SPRY domain superfamily	IPR043136	G3DSA:2.60.120.920
281	445	Homologous_superfamily	Concanavalin A-like lectin/glucanase domain superfamily	IPR013320	SSF49899
319	343	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
334	446	Domain	SPRY domain	IPR003877	SM00449
336	442	Domain	SPRY domain	IPR003877	PF00622
349	362	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
394	418	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
425	443	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0010468	regulation of gene expression	Biological Process	IBA	GO_REF:0000033
GO:0045087	innate immune response	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005813	centrosome	Cellular Component	IEA	GO_REF:0000044
GO:0005856	cytoskeleton	Cellular Component	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:25416956
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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