UBE2W

Details:

UniProt Entry: Q96B02
Gene: UBE2W
Class: Other E3 Components
Family: E2
Protein length: 151
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q96B02
MASMQKRLQK ELLALQNDPP PGMTLNEKSV QNSITQWIVD MEGAPGTLYE GEKFQLLFKF
SSRYPFDSPQ VMFTGENIPV HPHVYSNGHI CLSILTEDWS PALSVQSVCL SIISMLSSCK
EKRRPPDNSF YVRTCNKNPK KTKWWYHDDT C

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	151	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	G3DSA:3.10.110.10
3	151	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PS50127
4	144	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	SSF54495
6	119	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	cd00195
7	140	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PF00179

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006513	protein monoubiquitination	Biological Process	IEA	GO_REF:0000117
GO:0031669	cellular response to nutrient levels	Biological Process	IDA	PMID:12747827
GO:0038202	TORC1 signaling	Biological Process	IDA	PMID:12747827
GO:0140374	antiviral innate immune response	Biological Process	IDA	PMID:35893676
GO:0000209	protein polyubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0006281	DNA repair	Biological Process	IEA	GO_REF:0000043
GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	Biological Process	ISS	GO_REF:0000024
GO:0006974	DNA damage response	Biological Process	IEA	GO_REF:0000043
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	ISS	GO_REF:0000024
GO:0070979	protein K11-linked ubiquitination	Biological Process	IDA	PMID:20061386
GO:0071218	cellular response to misfolded protein	Biological Process	ISS	GO_REF:0000024
GO:1904262	negative regulation of TORC1 signaling	Biological Process	IDA	PMID:35927303
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IC	PMID:35893676
GO:0005654	nucleoplasm	Cellular Component	TAS	Reactome:R-HSA-8852130
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0031625	ubiquitin protein ligase binding	Molecular Function	IEA	GO_REF:0000117
GO:0061631	ubiquitin conjugating enzyme activity	Molecular Function	IEA	GO_REF:0000117
GO:0000166	nucleotide binding	Molecular Function	IEA	GO_REF:0000043
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IEA	GO_REF:0000107
GO:0005515	protein binding	Molecular Function	IPI	PMID:19549727
GO:0005524	ATP binding	Molecular Function	IEA	GO_REF:0000043

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