SPSB4

Details:

UniProt Entry: Q96A44
Gene: SPSB4
Class: Other E3 Components
Family: Receptor
Protein length: 273
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q96A44
MGQKLSGSLK SVEVREPALR PAKRELRGAE PGRPARLDQL LDMPAAGLAV QLRHAWNPED
RSLNVFVKDD DRLTFHRHPV AQSTDGIRGK VGHARGLHAW QINWPARQRG THAVVGVATA
RAPLHSVGYT ALVGSDAESW GWDLGRSRLY HDGKNQPGVA YPAFLGPDEA FALPDSLLVV
LDMDEGTLSF IVDGQYLGVA FRGLKGKKLY PVVSAVWGHC EVTMRYINGL DPEPLPLMDL
CRRSIRSALG RQRLQDISSL PLPQSLKNYL QYQ

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
34	245	Homologous_superfamily	Concanavalin A-like lectin/glucanase domain superfamily	IPR013320	SSF49899
34	233	Domain	B30.2/SPRY domain	IPR001870	PS50188
59	225	Homologous_superfamily	B30.2/SPRY domain superfamily	IPR043136	G3DSA:2.60.120.920
95	230	Domain	SPRY domain	IPR003877	SM00449
98	223	Domain	SPRY domain	IPR003877	PF00622
233	271	Domain	SOCS box domain	IPR001496	PF07525
233	273	Domain	SOCS box domain	IPR001496	PS50225
234	273	Domain	SOCS box domain	IPR001496	SM00969
235	272	Homologous_superfamily	SOCS box-like domain superfamily	IPR036036	SSF158235

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IEA	GO_REF:0000117
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000117
GO:0035556	intracellular signal transduction	Biological Process	IEA	GO_REF:0000002
GO:0042752	regulation of circadian rhythm	Biological Process	IMP	PMID:26392558
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0048511	rhythmic process	Biological Process	IEA	GO_REF:0000043
GO:1902916	positive regulation of protein polyubiquitination	Biological Process	IDA	PMID:28931592
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000120
GO:0019005	SCF ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IEA	GO_REF:0000117
GO:0005515	protein binding	Molecular Function	IPI	PMID:15601820

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