RN166

Details:

UniProt Entry: Q96A37
Gene: RNF166
Class: RING
Family: RING4
Protein length: 237
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q96A37
MAMFRSLVAS AQQRQPPAGP AGGDSGLEAQ YTCPICLEVY HRPVAIGSCG HTFCGECLQP
CLQVPSPLCP LCRLPFDPKK VDKATHVEKQ LSSYKAPCRG CNKKVTLAKM RVHISSCLKV
QEQMANCPKF VPVVPTSQPI PSNIPNRSTF ACPYCGARNL DQQELVKHCV ESHRSDPNRV
VCPICSAMPW GDPSYKSANF LQHLLHRHKF SYDTFVDYSI DEEAAFQAAL ALSLSEN

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
23	127	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
33	72	Domain	Zinc finger, RING-type	IPR001841	SM00184
33	73	Domain	Zinc finger, RING-type	IPR001841	PS50089
49	58	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
93	124	Domain	Zinc finger C2HC RNF-type	IPR034734	PF18574
98	117	Domain	Zinc finger C2HC RNF-type	IPR034734	PS51803
149	208	Domain	Drought induced 19 protein type, zinc-binding domain	IPR008598	PF05605

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0000209	protein polyubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0002376	immune system process	Biological Process	IEA	GO_REF:0000043
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0006914	autophagy	Biological Process	IEA	GO_REF:0000043
GO:0045087	innate immune response	Biological Process	IEA	GO_REF:0000043
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000044
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000003
GO:0005515	protein binding	Molecular Function	IPI	PMID:19549727
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043

Enzyme–Substrate Interactions ▾

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