UBE2F

Details:

UniProt Entry: Q969M7
Gene: UBE2F
Class: Other E3 Components
Family: E2
Protein length: 185
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q969M7
MLTLASKLKR DDGLKGSRTA ATASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN
KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL
REHSIDGTGW APTRTLKDVV WGLNSLFTDL LNFDDPLNIE AAEHHLRDKE DFRNKVDDYI
KRYAR

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
18	184	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	SSF54495
19	185	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	G3DSA:3.10.110.10
32	185	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PS50127
35	180	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	cd00195
37	179	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PF00179
105	120	Active_site	Ubiquitin-conjugating enzyme, active site	IPR023313	PS00183

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0000209	protein polyubiquitination	Biological Process	IEA	GO_REF:0000117
GO:0045116	protein neddylation	Biological Process	IEA	GO_REF:0000117
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:22190037
GO:0045087	innate immune response	Biological Process	IDA	PMID:22915799
GO:0051607	defense response to virus	Biological Process	IDA	PMID:22915799
GO:0043687	post-translational protein modification	Biological Process	TAS	Reactome:R-HSA-597592
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005829	cytosol	Cellular Component	IBA	GO_REF:0000033
GO:0000166	nucleotide binding	Molecular Function	IEA	GO_REF:0000043
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IEA	GO_REF:0000117
GO:0005524	ATP binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0019788	NEDD8 transferase activity	Molecular Function	IEA	GO_REF:0000117
GO:0005515	protein binding	Molecular Function	IPI	PMID:19250909
GO:0061654	NEDD8 conjugating enzyme activity	Molecular Function	IDA	PMID:19250909
GO:0061663	NEDD8 ligase activity	Molecular Function	IEA	GO_REF:0000003

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