ASB12

Details:

UniProt Entry: Q8WXK4
Gene: ASB12
Class: Other E3 Components
Family: Receptor
Protein length: 309
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q8WXK4
MNLMDITKIF SLLQPDKEEE DTDTEEKQAL NQAVYDNDSY TLDQLLRQER YKRFINSRSG
WGVPGTPLRL AASYGHLSCL QVLLAHGADV DSLDVKAQTP LFTAVSHGHL DCVRVLLEAG
ASPGGSIYNN CSPVLTAARD GAVAILQELL DHGAEANVKA KLPVWASNIA SCSGPLYLAA
VYGHLDCFRL LLLHGADPDY NCTDQGLLAR VPRPRTLLEI CLHHNCEPEY IQLLIDFGAN
IYLPSLSLDL TSQDDKGIAL LLQARATPRS LLSQVRLVVR RALCQAGQPQ AINQLDIPPM
LISYLKHQL

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
8	244	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	SSF48403
13	265	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
30	123	Repeat	Ankyrin repeat	IPR002110	PF12796
66	92	Repeat	Ankyrin repeat	IPR002110	SM00248
66	95	Repeat	Ankyrin repeat	IPR002110	PS50088
96	125	Repeat	Ankyrin repeat	IPR002110	SM00248
96	122	Repeat	Ankyrin repeat	IPR002110	PS50088
129	158	Repeat	Ankyrin repeat	IPR002110	SM00248
129	161	Repeat	Ankyrin repeat	IPR002110	PS50088
171	200	Repeat	Ankyrin repeat	IPR002110	SM00248
175	199	Repeat	Ankyrin repeat	IPR002110	PF00023
175	203	Repeat	Ankyrin repeat	IPR002110	PS50088
217	243	Repeat	Ankyrin repeat	IPR002110	SM00248
267	306	Domain	SOCS box domain	IPR001496	PF07525
268	308	Domain	SOCS box domain	IPR001496	SM00969

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8952039
GO:0000151	ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:16325183

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