ASB13

Details:

UniProt Entry: Q8WXK3
Gene: ASB13
Class: Other E3 Components
Family: Receptor
Protein length: 278
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q8WXK3
MEPRAADGCF LGDVGFWVER TPVHEAAQRG ESLQLQQLIE SGACVNQVTV DSITPLHAAS
LQGQARCVQL LLAAGAQVDA RNIDGSTPLC DACASGSIEC VKLLLSYGAK VNPPLYTASP
LHEACMSGSS ECVRLLIDVG ANLEAHDCHF GTPLHVACAR EHLDCVKVLL NAGANVNAAK
LHETALHHAA KVKNVDLIEM LIEFGGNIYA RDNRGKKPSD YTWSSSAPAK CFEYYEKTPL
TLSQLCRVNL RKATGVRGLE KIAKLNIPPR LIDYLSYN

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
17	241	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
18	47	Repeat	Ankyrin repeat	IPR002110	SM00248
18	50	Repeat	Ankyrin repeat	IPR002110	PS50088
18	223	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	SSF48403
24	112	Repeat	Ankyrin repeat	IPR002110	PF12796
51	80	Repeat	Ankyrin repeat	IPR002110	SM00248
51	83	Repeat	Ankyrin repeat	IPR002110	PS50088
84	113	Repeat	Ankyrin repeat	IPR002110	SM00248
84	112	Repeat	Ankyrin repeat	IPR002110	PS50088
85	100	Repeat	Ankyrin repeat	IPR002110	PR01415
116	148	Repeat	Ankyrin repeat	IPR002110	PS50088
116	145	Repeat	Ankyrin repeat	IPR002110	SM00248
121	212	Repeat	Ankyrin repeat	IPR002110	PF12796
149	178	Repeat	Ankyrin repeat	IPR002110	SM00248
149	181	Repeat	Ankyrin repeat	IPR002110	PS50088
165	179	Repeat	Ankyrin repeat	IPR002110	PR01415
181	213	Repeat	Ankyrin repeat	IPR002110	PS50088
181	210	Repeat	Ankyrin repeat	IPR002110	SM00248
234	278	Domain	SOCS box domain	IPR001496	PS50225
235	277	Homologous_superfamily	SOCS box-like domain superfamily	IPR036036	SSF158235
237	278	Domain	Ankyrin repeat and SOCS box protein 13, SOCS box domain	IPR037334	cd03729
238	275	Domain	SOCS box domain	IPR001496	PF07525
239	278	Domain	SOCS box domain	IPR001496	SM00969

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0035556	intracellular signal transduction	Biological Process	IEA	GO_REF:0000002
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000117
GO:0005515	protein binding	Molecular Function	IPI	PMID:16169070

Data Usage Statement and License Agreement

Ownership and Copyright

The Database, including all associated datasets, metadata, and documentation, is the intellectual property of the PROXIDRUGs consortium and the InnoDATA project.
The content of the Database is protected under applicable copyright and database protection laws.

Permitted Use

The Database is provided for research, academic, and non-commercial purposes only, unless explicitly stated otherwise.
Users are permitted to:
- Access, download, and use the data.
- Modify or build upon the data for academic, educational, or scientific purposes.
- Share derived datasets, analyses, or visualizations with proper citation and explicit acknowledgment of “The Human E3 Ligome” project.

Prohibited Use

Use the Database or any derivative works for commercial purposes without prior written consent from the PROXIDRUGs consortia (InnoDATA PIs).
Redistribute or republish the Database (or substantial parts of it) without proper credit and adherence to the license terms.
Misrepresent the data, alter metadata to mislead, or use it in a way that violates ethical or scientific standards.

Licensing

Unless otherwise stated, the Database is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0).
This license allows redistribution and adaptation, provided appropriate credit is given.
Contributions (e.g., data corrections, additions, or scripts) can be made through merge requests on GitLab.
Contributors must agree to license their contributions under the same CC BY 4.0 license.

Citation Requirements

If you use or refer to the Database in your publications, reports, or presentations, you must cite the paper: Dutta et al. (2025, preprint)

Contact and Support

For inquiries, permissions, or support regarding the Database, please contact: Dr. Ramachandra M. Bhaskara, Goethe University Frankfurt.
Email: bhaskara@med.uni-frankfurt.de.
Website maintained by Alberto Cristiani, Arghya Dutta, and Siddhanta V. Nikte.