ASB11

Details:

UniProt Entry: Q8WXH4
Gene: ASB11
Class: Other E3 Components
Family: Receptor
Protein length: 323
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q8WXH4
MEDGPVFYGF KNIFITMFAT FFFFKLLIKV FLALLTHFYI VKGNRKEAAR IAEEIYGGIS
DCWADRSPLH EAAAQGRLLA LKTLIAQGVN VNLVTINRVS SLHEACLGGH VACAKALLEN
GAHVNGVTVH GATPLFNACC SGSAACVNVL LEFGAKAQLE VHLASPIHEA VKRGHRECME
ILLANNVNID HEVPQLGTPL YVACTYQRVD CVKKLLELGA SVDHGQWLDT PLHAAARQSN
VEVIHLLTDY GANLKRRNAQ GKSALDLAAP KSSVEQALLL REGPPALSQL CRLCVRKCLG
RACHQAIHKL HLPEPLERFL LYQ

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
39	281	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	SSF48403
63	286	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
64	93	Repeat	Ankyrin repeat	IPR002110	SM00248
64	96	Repeat	Ankyrin repeat	IPR002110	PS50088
69	157	Repeat	Ankyrin repeat	IPR002110	PF12796
97	129	Repeat	Ankyrin repeat	IPR002110	PS50088
97	126	Repeat	Ankyrin repeat	IPR002110	SM00248
130	162	Repeat	Ankyrin repeat	IPR002110	PS50088
130	159	Repeat	Ankyrin repeat	IPR002110	SM00248
162	190	Repeat	Ankyrin repeat	IPR002110	PS50088
162	191	Repeat	Ankyrin repeat	IPR002110	SM00248
165	223	Repeat	Ankyrin repeat	IPR002110	PF12796
195	224	Repeat	Ankyrin repeat	IPR002110	SM00248
195	223	Repeat	Ankyrin repeat	IPR002110	PS50088
227	256	Repeat	Ankyrin repeat	IPR002110	SM00248
230	259	Repeat	Ankyrin repeat	IPR002110	PS50088
230	280	Repeat	Ankyrin repeat	IPR002110	PF13637
273	323	Domain	SOCS box domain	IPR001496	PS50225
280	322	Homologous_superfamily	SOCS box-like domain superfamily	IPR036036	SSF158235
282	323	Domain	Ankyrin repeat and SOCS box protein 9/11, SOCS box domain	IPR037333	cd03728
284	321	Domain	SOCS box domain	IPR001496	PF07525
284	323	Domain	SOCS box domain	IPR001496	SM00969

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0030968	endoplasmic reticulum unfolded protein response	Biological Process	IDA	PMID:31387940
GO:0035556	intracellular signal transduction	Biological Process	IEA	GO_REF:0000002
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:31387940
GO:0045732	positive regulation of protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0070979	protein K11-linked ubiquitination	Biological Process	IDA	PMID:38574733
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0005783	endoplasmic reticulum	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000117
GO:0031466	Cul5-RING ubiquitin ligase complex	Cellular Component	IDA	PMID:31387940
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IDA	PMID:24337577

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