RN133

Details:

UniProt Entry: Q8WVZ7
Gene: RNF133
Class: RING
Family: RING3
Protein length: 376
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q8WVZ7
MHLLKVGTWR NNTASSWLMK FSVLWLVSQN CCRASVVWMA YMNISFHVGN HVLSELGETG
VFGRSSTLKR VAGVIVPPEG KIQNACNPNT IFSRSKYSET WLALIERGGC TFTQKIKVAT
EKGASGVIIY NVPGTGNQVF PMFHQAFEDV VVVMIGNLKG TEIFHLIKKG VLITAVVEVG
RKHIIWMNHY LVSFVIVTTA TLAYFIFYHI HRLCLARIQN RRWQRLTTDL QNTFGQLQLR
VVKEGDEEIN PNGDSCVICF ERYKPNDIVR ILTCKHFFHK NCIDPWILPH GTCPICKCDI
LKVLGIQVVV ENGTEPLQVL MSNELPETLS PSEEETNNEV SPAGTSDKVI HVEENPTSQN
NDIQPHSVVE DVHPSP

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
75	161	Domain	PA domain	IPR003137	PF02225
102	135	Homologous_superfamily	PA domain superfamily	IPR046450	SSF52025
232	303	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
254	297	Domain	Zinc finger, RING-type	IPR001841	PF13639
256	297	Domain	Zinc finger, RING-type	IPR001841	PS50089
256	296	Domain	Zinc finger, RING-type	IPR001841	SM00184

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0051865	protein autoubiquitination	Biological Process	IEA	GO_REF:0000107
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005770	late endosome	Cellular Component	IBA	GO_REF:0000033
GO:0005783	endoplasmic reticulum	Cellular Component	IBA	GO_REF:0000033
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IBA	GO_REF:0000033
GO:0005794	Golgi apparatus	Cellular Component	IBA	GO_REF:0000033
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000003

Enzyme–Substrate Interactions ▾

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