RN217

Details:

UniProt Entry: Q8TC41
Gene: RNF217
Class: RBR
Family: RBR
Protein length: 542
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q8TC41
MGEEQSTVSG GGGPQESQTL ASGTAGHPEP PRPQGDSARA PPLRAASAEP SGGGCGSDWG
CADTSAPEPA RSLGPPGWSK SRAPAQPAGL ALTGPLNPQT LPLQLELEEE EEEAGDRKEG
GDEQQEAPPG EELEPRTRVG AADGLVLDVL GQRRPSLAKR QVFCSVYCVE SDLPEAPASE
QLSPPASPPG APPVLNPPST RSSFPSPRLS LPTDSLSPDG GSIELEFYLA PEPFSMPSLL
GAPPYSGLGG VGDPYVPLMV LMCRVCLEDK PIKPLPCCKK AVCEECLKVY LSAQVQLGQV
EIKCPITECF EFLEETTVVY NLTHEDSIKY KYFLELGRID SSTKPCPQCK HFTTFKKKGH
IPTPSRSESK YKIQCPTCQF VWCFKCHSPW HEGVNCKEYK KGDKLLRHWA SEIEHGQRNA
QKCPKCKIHI QRTEGCDHMT CSQCNTNFCY RCGERYRQLR FFGDHTSNLS IFGCKYRYLP
ERPHLRRLVR GSVCAGKLFI APLIMVLGLA LGAIAVVIGL FVFPIYCLCK KQRKRSRTGM
HW

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
177	473	Family	E3 ubiquitin ligase RBR family	IPR031127	PTHR11685
259	478	Domain	TRIAD supradomain	IPR044066	PS51873
260	338	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
328	396	Domain	IBR domain	IPR002867	SM00647
340	396	Domain	IBR domain	IPR002867	PF01485
403	474	Domain	IBR domain	IPR002867	SM00647
412	456	Domain	IBR domain	IPR002867	PF01485

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000002
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	ISS	GO_REF:0000024
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-983140
GO:0000151	ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IEA	GO_REF:0000002
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000003
GO:0031624	ubiquitin conjugating enzyme binding	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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