FBX30

Details:

UniProt Entry: Q8TB52
Gene: FBXO30
Class: RING
Family: RING1
Protein length: 745
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: Complex
AlphaFold Model: Link
PDB Structures: 2yre

Protein Sequence ▾

>Q8TB52
MEEELQHSHC VNCVSRRCMT RPEPGISCDL IGCPLVCGAV FHSCKADEHR LLCPFERVPC
LNSDFGCPFT MARNKVAEHL EMCPASVVCC TMEWNRWPVS YADRKSYENL SRDVDEVAQL
DMALALQDQR MLLESLKVAT MMSKATDKVS KPREQISVKS SVPEIPHANG LVSVDEESYG
ALYQATVETT RSLAAALDIL NTATRDIGML NTSVPNDMDE QQNARESLED QNLKDQDHLY
EEEIGAVGGI DYNDTNQNAQ SEQNGSSDLL CDLNTSSYDT SALCNGFPLE NICTQVIDQN
QNLHGDSKQS NLTNGDCVAS SDGTSKPSSS LAVAAQLREI IPSSALPNGT VQHILMPDDE
GEGELCWKKV DLGDVKNVDV LSFSHAPSFN FLSNSCWSKP KEDKAVDTSD LEVAEDPMGL
QGIDLITAAL LFCLGDSPGG RGISDSRMAD IYHIDVGTQT FSLPSAILAT STMVGEIASA
SACDHANPQL SNPSPFQTLG LDLVLECVAR YQPKQRSMFT FVCGQLFRRK EFSSHFKNVH
GDIHAGLNGW MEQRCPLAYY GCTYSQRRFC PSIQGAKIIH DRHLRSFGVQ PCVSTVLVEP
ARNCVLGLHN DHLSSLPFEV LQHIAGFLDG FSLCQLSCVS KLMRDVCGSL LQSRGMVILQ
WGKRKYPEGN SSWQIKEKVW RFSTAFCSVN EWKFADILSM ADHLKKCSYN VVEKREEAIP
LPCMCVTREL TKEGRSLRSV LKPVL

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
2	744	Family	F-box only protein 30/40	IPR031890	PTHR15933
6	55	Homologous_superfamily	Zinc finger, TRAF-type, N-terminal	IPR043013	G3DSA:3.30.40.150
7	99	Domain	Zinc finger, TRAF-type	IPR001293	PF15965
49	91	Domain	Zinc finger, TRAF-type	IPR001293	PS50145
56	105	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
608	654	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
610	646	Domain	F-box domain	IPR001810	PS50181
610	724	Domain	F-box domain	IPR001810	PF15966

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006325	chromatin organization	Biological Process	IEA	GO_REF:0000107
GO:0007059	chromosome segregation	Biological Process	IEA	GO_REF:0000107
GO:0010467	gene expression	Biological Process	IEA	GO_REF:0000107
GO:0030261	chromosome condensation	Biological Process	IEA	GO_REF:0000107
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8952618
GO:0005515	protein binding	Molecular Function	IPI	PMID:28514442
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000002

Enzyme–Substrate Interactions ▾


P13631	RARG	Yes	No	No	No	—	No	E3-specific

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